... modulates apoptotic responses to tumor necrosis factor- and Fas ligand but does not suppress expression of receptors of the tumor necrosis factor receptor superfamily. Exp Hematol 27: 1–8 . Konopleva, ... predisposition to osteosarcoma (Aziz et al. Cancer Prevention – From Mechanisms to Translational Benefits 18and Gillies, 2004). Hypoxia-inducible factors (HIFs) are master regulators of cell ... and lung cancer, but was more delayed for stomach, colorectal, and prostate cancer. For lung and esophageal cancer, benefit was confined to adenocarcinomas. Benefit was unrelated to aspirin...