... terms of pr evention and treatment, there areseveral limitations to be discussed. First, the molecular mechanisms underlying the effects of GH on the devel-opment of AFLD in the presence of alcohol ... evels,and therefore enhance the oxidation of lipid substratesand result in insulin resistance. Furthermore, the safetyand potential toxicity of GH gene therapy should not beneglected. Therefore, ... inaccordance with the guidelines of the National Institutes of Health (Bethesda , MD, USA) and the Chinese Peo-ple’s Liberation Army General Hospital for the humanetreatment of laboratory animals.Mice...