... carried out and coordinated the study, immunohisto-chemical examinations of tumor specimens and dataanalysis, and drafted the manuscript. ZYZ and JF partici-pated in the interpretation of data, ... immunohistochemistry and examined the expression of the 3 proteins in 7 pairs of HCC tissues and the adjacent hepatic tissues by using western blotanalysis.Results: The expression of p53, p21/WAF1, and MDM2 ... theexpression of p53, p21/WAF1, and MDM2 in 181 pairs of HCC on the basis of different clinical parameters, includ-ing the gender, age, tumor size, number of tumors,HBsAg, pathologic grade, and serum...