... participated in advisory boards of Pfizer, Astellas, and Bayer and has received lecture honoraria from Merck, Pfizer, AstraZeneca, Astellas,Cipla, Novartis, and Glenmark.Received: 19 April 2011 Accepted: ... infections caused by gram-negative bacteria.Antimicrob Agents Chemother 2009, 53:3430-3436.15. Daikos GL, Skiada A, Pavleas J, Vafiadi C, Salatas K, Tofas P, Tzanetou K,Markogiannakis A, Thomopoulos ... optimal dosing regimen. Although pharmacokinetic and pharmacodynamic data in ICU patients are scarce,recent evidence shows that the pharmacokinetics/pharmacodynamics of colistimethate sodium and...