... tissues. (A) The presence of b1Bin Purkinje cells (large arrowheads) and intheir processes (small arrowheads) of the cerebellum. (B) Specific b1Blabeling was abolished in the Purkinje cells (arrowhead) ... placenta, lung, liver, kidney and pancreas. Inhuman brain, the b1Btranscript was most abundant in the cerebellum, followed by the cerebral cortex and occipitallobe (Fig. 2B). The overall ... able to modulatealmost all aspects of the channel properties, includingvoltage dependent gating, activation and inactivation, aswell as greatly increasing the number of functional channelspresent...