báo cáo hóa học:" Isolated cystic tuberculosis of scapula; case report and review of literature" docx

Báo cáo hóa học: "DNA polymeraseh protein expression predicts treatment response and survival of metastatic gastric adenocarcinoma patients treated with oxaliplatin-based chemotherapy" pot

Báo cáo hóa học: "DNA polymeraseh protein expression predicts treatment response and survival of metastatic gastric adenocarcinoma patients treated with oxaliplatin-based chemotherapy" pot

... design of the study. RZL and HZZ reviewed the IHC slices. ZQW and YHL participated in the statistical analysis. RHX conceived of the study, and participated in its design and coordination and helped ... chemo therapy. With this standard, only 23 patients had positiv e expression, with 7 out of 62 clinical benefit cases (CR+PR+SD) from chemother- apy and 16 out of 18 PD cas...
Ngày tải lên : 18/06/2014, 16:20
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báo cáo hóa học:" Lentivirus-mediated RNAi silencing targeting ABCC2 increasing the sensitivity of a human nasopharyngeal carcinoma cell line against cisplatin" docx

báo cáo hóa học:" Lentivirus-mediated RNAi silencing targeting ABCC2 increasing the sensitivity of a human nasopharyngeal carcinoma cell line against cisplatin" docx

... level of ABCC2 mRNA expression for about 72%, and named as CNE2/ shABCC2-1 and -2, respectively (Fig. 1B). To further confirm the specificity of siRNA-mediated silencing of ABCC2, the detection of ... calibration curve was y = 1.59x + 17.917(y stands for peak height of cisplatin and x stands for concentration of cisplatin). Based on this equation, the concentration of cisp...
Ngày tải lên : 18/06/2014, 15:20
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báo cáo hóa học:" Tremorgenesis: a new conceptual scheme using reciprocally innervated circuit of neurons" pptx

báo cáo hóa học:" Tremorgenesis: a new conceptual scheme using reciprocally innervated circuit of neurons" pptx

... One of the reasons is our lack of under- standing in the pathogenesis and natural history of several tremor disorders. Current theories suggest that tremor is driven by complex combinations of ... models of tremor [7]. This is the case for instance with the model of acute administra- tion of harmaline in rodents [8], widely used to mimic essential tremor, or for the animal m...
Ngày tải lên : 18/06/2014, 15:20
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báo cáo hóa học:" Sigma-2 receptor ligands potentiate conventional chemotherapies and improve survival in models of pancreatic adenocarcinoma" ppt

báo cáo hóa học:" Sigma-2 receptor ligands potentiate conventional chemotherapies and improve survival in models of pancreatic adenocarcinoma" ppt

... a variety of human and rodent tumors [5,6,10,11] and that synthetic ligands to this receptor could play an important role in cancer diagnosis and therapy [12]. We have previ- ously reported that ... pancreas cancer and weakly expressed in nor- mal pancreas [13]. In this same study, we carefully charac- terized the receptor-ligand binding interaction and reported the Kd and Bmax...
Ngày tải lên : 18/06/2014, 15:20
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báo cáo hóa học:" Retinal pigment epithelial cells secrete neurotrophic factors and synthesize dopamine: possible contribution to therapeutic effects of RPE cell transplantation in Parkinson''''s disease" doc

báo cáo hóa học:" Retinal pigment epithelial cells secrete neurotrophic factors and synthesize dopamine: possible contribution to therapeutic effects of RPE cell transplantation in Parkinson''''s disease" doc

... assay. HPLC analysis of the synthesis and release of DA by RPE cellsFigure 5 HPLC analysis of the synthesis and release of DA by RPE cells.(A) HPLC analysis of standard of DA, 3,4-dihy- droxyphenylacetic ... designed by MM and WL and were per- formed by MM, XL, and XF. Human RPE cells were sepa- rated and cultured by QG. DY, LL and SC gave advises on the work and...
Ngày tải lên : 18/06/2014, 15:20
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Báo cáo hóa học: " Fowlpox virus recombinants expressing HPV-16 E6 and E7 oncogenes for the therapy of cervical carcinoma elicit humoral and cell-mediated responses in rabbits" pot

Báo cáo hóa học: " Fowlpox virus recombinants expressing HPV-16 E6 and E7 oncogenes for the therapy of cervical carcinoma elicit humoral and cell-mediated responses in rabbits" pot

... extraction and CTL assays. All the animals were housed and handled in accordance with the European guidelines no. 86/609/CEE and 116/92 for the protection of laboratory experimental animals and laboratory ... HPV-16 E6 and E7 oncogenes for the therapy of cervical carcinoma elicit humoral and cell-mediated responses in rabbits Journal of Translational Medi- cine 2010, 8:40...
Ngày tải lên : 18/06/2014, 16:20
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Báo cáo hóa học: " Strategy Escalation: An emerging paradigm for safe clinical development of T cell gene therapies Richard Paul Junghan" pdf

Báo cáo hóa học: " Strategy Escalation: An emerging paradigm for safe clinical development of T cell gene therapies Richard Paul Junghan" pdf

... molecular and biological fea- tures of the modified cells and the method of their proposed administration. This Commentary presents an example of such a discussion from the current state of the art ... (engraftment AND 2 nd generation) is too much risk. A 0 → Strategy 4 test presumes much about the quality of our knowledge of the potential normal tissue targets and their...
Ngày tải lên : 18/06/2014, 16:20
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Báo cáo hóa học: "IL-2 as a therapeutic target for the restoration of Foxp3+ regulatory T cell function in organ-specific autoimmunity: implications in pathophysiology and translation to human disease" doc

Báo cáo hóa học: "IL-2 as a therapeutic target for the restoration of Foxp3+ regulatory T cell function in organ-specific autoimmunity: implications in pathophysiology and translation to human disease" doc

... kground of the host, microflora and target tissue. As such, T reg depletion, or alterations of the foxp3 gene, as seen in Scurfy mice or IPEX patients, results in a loss of T reg cells, and catastrophic ... an efficient and timely targeting of activated Treg versus Teff cells during distinct p hases of T1 D progression. Several studies report the use of several strategies...
Ngày tải lên : 18/06/2014, 16:20
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Báo cáo hóa học: "Programmed cell death-1 (PD-1) at the heart of heterologous prime-boost vaccines and regulation of CD8+ T cell immunity" doc

Báo cáo hóa học: "Programmed cell death-1 (PD-1) at the heart of heterologous prime-boost vaccines and regulation of CD8+ T cell immunity" doc

... very well be at the heart of both the mechanism and advantage of heterologous prime- boost regimens. Therefore, the remainder of this review will focus on this key feature and its underlying mechanism, ... properties of non- replicating vectors and biological response modifiers by direct intra-nodal administration of plasmid and pepti de [19,41]. We showed that the sequenc...
Ngày tải lên : 18/06/2014, 16:20
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báo cáo hóa học: " Cardiac rehabilitation in Austria: long term health-related quality of life outcomes" pptx

báo cáo hóa học: " Cardiac rehabilitation in Austria: long term health-related quality of life outcomes" pptx

... the reduction of symptoms and the improvement of physical functioning and general wellbe- ing [1,2]. These outcomes are typically considered to be patient-reported outcomes (PRO) and have top-tier ... (QALYs) [24]. The EQ-5D consists of a 5-dimensional descriptive system and a visual analogue scale allowing assessment of relevant segments of HRQL: Health and Quality of L...
Ngày tải lên : 18/06/2014, 19:20
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