báo cáo hóa học:" Hemolymphangioma of the lower extremities in children: two case reports" docx

... manuscript. M.Vwas the surgeon of the second patient. A.K helped with the editing of the manuscript. KF, as the director of the orthopaedic department, guided usand helped in finalizing the manuscript.All ... on the anteromedial s ide of the lefttibia. The lesion had fine adhesions to the surroundingtissues and the cortex of the bone was found intact.En bloc resection was performed releasing the ... nature of the lesion, therefore should beordered in a routine base; the extension and the rela-tionship of the tumor to t he surrounding tissues israther depicted by the MRI [11]. The differential...

báo cáo hóa học: " Responsiveness of the EQ-5D in breast cancer patients in their first year after treatment" ppt

... beresponsive to meaningful changes in health in the patient population under investigation. The aim of this study was to investigate the responsiveness of the EQ-5D in breast cancer patients in theirfirst ... randommissings within the instruments (n = 19) or because theywere a study drop-out (n = 10). A total of 192 patientswere therefore included in the analysis. Their demo-graphic and clinical characteristics ... (improvements) in the subgroupsreporting improvements on global health. Accordingly,only a minor change on the EQ VAS and no change on the EQ-5D Index were reported in the no change subgroup of the EORTC...

báo cáo hóa học:" Study of the collagen structure in the superficial zone and physiological state of articular cartilage using a 3D confocal imaging technique" pptx

... sectioning and dehy-drating the AC, the 3D collagen network revealed in thisstudy closely represents the natural character of the colla-gen network in AC. Therefore, the changes observed in the 3D ... shearing resistance of the AC. It also leads to change of the osmotic pres-sure in AC and gradually release of PGs to the joint cavity. The tensile strength and lateral integrity of the interwoven ... AC in vivo [28-30]. Although the staining technique used in this study is not clinical appli-cable, our current study on the investigation of clinicalviable staining techniques for imaging the...

Báo cáo hóa học: " Study of the vertical transport in p-doped superlattices based on group III-V semiconductors" pdf

... verysmall. In the group-III arsenides, the minigap is shorterdue to the lower values of the effective masses. After NA=4×1012cm-2, the conductivity increases againbec ause of occupation of the ... been given in earlier studies, and it is mainlybased on the solution of the Boltzmann equation [4-6]. The use of SLs i s important since increasing the disper-sion relation of the minibands for ... behavior. At the beginning, the first miniband isonly partially occupied; once the band filling increases, i.e., as the Fermi level goes up to the first minibandvalue, the conductivity increases....

báo cáo hóa học:" Summary of the primer on tumor immunology and the biological therapy of cancer" ppt

... patients withmelanoma in combination with high dose IL-2 has beenshown to achieve clinical responses in the range of 50%.However, minimal activity of IL-2 in the treatment of other cancers has been ... generate large numbers of high aviditytumor-reactive CD8+ T cells in individual patients in timeand maintain their survival in vivo. The solution is genetherapy, by engineering T cells with high ... by APCs; the second is the binding of costimulatory ligands, expressed on APC, to receptorson the T cells. The discovery of multiple costimulatorymolecules that influence the course of T cell...

báo cáo hóa học:" Comparison of the effects of vitamin D products in a psoriasis plaque test and a murine psoriasis xenograft model" docx

... and ointment vehicle.Clinical rating was performed twice a week during the treatment phase assessing the Total Clinical Score (TCS). The Total Clinical Score is defined as the sum of erythema(0-3), ... demonstrates the feasibility of obtaining robustbiomarker data in the psoriasis plaque test that correlatewell with those obtained in other clinical studies. Further-more, the biomarker data from the ... the back of the animals. The split human keratome biopsies were then grafted onto the back of the animals. The grafts were protected by a band-age during the following two weeks. All the transplanta-tion...

Báo cáo hóa học: " Incidence of the V600K mutation among melanoma patients with BRAF mutations, and potential therapeutic response to the specific BRAF inhibitor PLX4032" potx

... in culture; HMK,participated in writing of the manuscript; DN, excised tumors and provided the material for research; RH, in charge of analyzing tumor specimens andparticipated in writing the ... between the V600E and V600K mutations. Ourpreclinical data demonstrating s imilar kinase activity of the V600K and V600E mutations, together with clearevidence of clinical activity of PLX4032 in ... specific genetic composition of the tumor [5].One of our patients with locally advanced unresectablemelanoma inv olving the skin of the l eft chest wall, pro-gressing after treatment with topical...

Báo cáo hóa học: " Modulation of the major histocompatibility complex by neural stem cell-derived neurotrophic factors used for regenerative therapy in a rat model of stroke" ppt

... significant increase of NGF, BDNF and NT-3 transcripts and NGF proteins in both the NSCcultures and the CSF of the rats. The immunochemical staining for MHC in brain sections and the enzyme-linkedimmunosorbent ... staining.Immunohistochemistry stainingImmunohistochemical staining of nestin and BrdU wereperformed to assess the property of NSC in cultures andtrack the migration and homing of allogeneic BrdU-labeled NSC in the host ... futurestudies.Conclusions The findings presented here provide further insights into the mechanisms of NSC in the regeneration of the CNS.Should the MHC modulation mediated by NSC-derivedneurotrophins be elucidated,...

Báo cáo hóa học: " Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer" ppt

... implicated in cisplatin resistance, i.e.decreased drug uptake, insufficient DNA-binding of the drug, increased DNA-repair of cisplatin adducts and fail-ure of induction of apoptosis, reviewed in [2,5,7]. The ... predict cisplatin response in EOC. Further studiesare required to evaluate the role of RBM3 in predictingrespons e to other platinum based agents, particularly in the setting of a prospective ... importantrole in the stabilization of mRNA by reversibly bindingto conserved sequence elements, most often AU-richelements (AREs), in the untranslated regions (UTRs) of the mRNA resulting in either...

Báo cáo hóa học: " Prevalence of the GJB2 IVS1+1G A mutation in Chinese hearing loss patients with monoallelic pathogenic mutation in the coding region of GJB2" pot

... detected in an individual of the Uygur ethnic minority.We did not find the 309-kb deletion of GJB6 in any of the 212 patients with monoallelic GJB2 coding regionmutation or in any of the 105 ... orother noncoding regions of GJB2.To evaluate the impact of the IVS1+1G>A splice-sitemutation and the b asal promoter region in the noncod-ingpartoftheGJB2geneamongChinesepatients,weinitially ... mutation in the GJB2 genewith either rece ssive or unclear pathogenicity, despitedirect sequencing of the entire coding region of the gene [12-14]. The ratio of a 309-kb deletion involving the GJB6...

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