báo cáo hóa học:" The caveolae-mediated sv40 entry pathway bypasses the golgi complex en route to the endoplasmic reticulum" doc

... JournalOpen AccessResearch The caveolae-mediated sv40 entry pathway bypasses the golgi complex en route to the endoplasmic reticulumLeonard C Norkin* and Dmitry KuksinAddress: Department of ... clath-rin-independent mode of endocytosis likely enables theseligands to access sites that can not be accessed from the clathrin-dependent endocytic pathway. SV40 binds to major histocompatibility complex (MHC)class ... pit-mediated pathway and the caveolae-mediated pathway do not mix or intersect at any point.Importantly, CT traffics through the Golgi en route to the ER [16]. Transport of the toxin from the Golgi to the...

Báo cáo sinh học: " The caveolae-mediated sv40 entry pathway bypasses the golgi complex en route to the endoplasmic reticulu" doc

... caveolin-1-independent endocyto-BioMed CentralPage 1 of 6(page number not for citation purposes)Virology JournalOpen AccessResearch The caveolae-mediated sv40 entry pathway bypasses the golgi complex en route ... clath-rin-independent mode of endocytosis likely enables theseligands to access sites that can not be accessed from the clathrin-dependent endocytic pathway. SV40 binds to major histocompatibility complex (MHC)class ... pit-mediated pathway and the caveolae-mediated pathway do not mix or intersect at any point.Importantly, CT traffics through the Golgi en route to the ER [16]. Transport of the toxin from the Golgi to the...

báo cáo hóa học:" Regulation of FeLV-945 by c-Myb binding and CBP recruitment to the LTR" doc

... suggest that the ability of the 21-bp triplication to enhance transcription preferentially inhematopoietic cells depends on the presence of the adja-cent LTR binding sites in their natural ... through the 21-bp triplication is apparentlyinsufficient to regulate transcription in the absence of the normally adjacent LTR enhancer and promoter. Thesefindings are consistent with the possibility ... copies asin the 21-bp triplication. Thus, the affinity of binding to the triplication may be higher than to the competitor. It isfurther known that sequences flanking the consensusbinding...

báo cáo hóa học: " Health-related quality of life in children with cystic fibrosis: validation of the German CFQ-R" potx

... itemseems to be relevant to the content. This content and itsmeaningfulness to the patient, the face validity, can beconsidered more important than a mathematical linkage.With respect to content ... between patients of the intervention and control groups might have beenobserved if the investigators had used the CFQ-R, Childversion in addition. The findings of the current study underline the ... according to parents' and patients report. The questionnaires were used before the physician wasconsulted. In the test-retest sample, the second surveytook place either at the patient's...

báo cáo hóa học: " Indoors illumination and seasonal changes in mood and behavior are associated with the health-related quality of life" pdf

... Interest in the assessmentand significance of the HRQoL has increased in recentyears [6]. The shortening length of the day tends to affect mentalwell-being [7] and to trigger the occurrence of ... and mental health and abilities,are known to be linked to distress but occur to one duringdifferent schedules. Therefore, even if there were no phys-iological pathway from the habitat to the ... has been linked to the occurrence of the seasonal changes, we wanted to know whetherillumination indoors contributes to the HRQoL.Methods: Of the sample of 7979 individuals, being representative...

báo cáo hóa học: " Adalimumab improves health-related quality of life in patients with moderate to severe plaque psoriasis compared with the United States general population norms: Results from a randomized, controlled Phase III study" pdf

... moderate to severe psoriasis. The difference in MCS scores between the REVEAL and the MEPS samples were 3.1 to 3.4 points,which exceeded the MCID of 3.0 points. This finding isnot surprising given ... between REVEAL study groupsand the general US population; however this finding maynot be due to the nature of disease impact on physicalaspects of health, but rather to the method used to derivePCS ... scales, the greatest baseline to endpoint improvements (range of trial durations: 10 to 16 weeks) were seen in the Bodily Pain and Social Functionscales. These findings are also consistent with...

Báo cáo hóa học: " Health-related quality of life of child and adolescent retinoblastoma survivors in the Netherlands" ppt

... HRQoL compared with the Dutch reference group. The perceptions related to HRQoL differ substantially between parents and their children, i.e. parents judge the HRQoL of their child to be relatively ... comple-tion of the KIDSCREEN questionnaire, and checked the completeness of it. We determined whether the childrenhad completed the KIDSCREEN questionnaire them-selves, by simply asking the children individually ... appointment for a homevisit. The KIDSCREEN questionnaires [12] were sent bypost, with the instruction for the children to completethem alone and independently from other family mem-bers. In case...

báo cáo hóa học: " Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: Evidence for an immune-modulated glutamatergic neurotransmission?" doc

... depression[13]. This hypothesis is based on the observation that the above mentioned proinflammatory cytokines inducea shift from serotonin synthesis to tryptophanmetabolism via the kynurenine pathway in ... (QUIN). These substances are endogenous modulators of NMDA glutamate receptors. A key enzyme of the kynurenine pathway, indoleamine 2,3-dioxygenase (IDO), and the enzyme that catalyses the production ... months prior to death; (3) the presentstudy enables us to draw conclusions about the cellularQUIN content, but not released or secreted QUIN in the extracellular space, which potential ly interferes...

báo cáo hóa học: " A case report of acute dermatitis that developed during an experiment examining the bromination of 3-hexylthiophene" potx

... compounds have been seen in the perfume indus-try and among aromatherapists[1,2]. However, itremains difficult to identify the chemica ls responsible ofdermatitis from the complex contents of volatile ... condu cted another organic synthesisexperiment, but had no symptoms. The latter experi-ment was conducted inside a d ifferent fume hood thatwas sufficiently distant from the case to avoid exposu ... 2,4,5-tri-bromo-3-hexylthiophene. The volumes of theseproducts were probably small. The experiment was terminated on Day 3. His skinsymptoms worsened further (Figures 1 and 2). On Day 8,a dermatologist diagnosed them...

báo cáo hóa học: " Work-related stress and bullying: gender differences and forensic medicine issues in the diagnostic procedure" pdf

... of these elements should be com-mitted to the occupational doctor and/or to the inspec-tion staff of th e insurance agency. The expert in charge,after the suit has come to court, has often to ... inorder to plan appropriate interventions. A document of the same agency emphasizes that, compared to men,research, prevention and awareness of the risks of work-ing women have been underestimated ... perceived ability to defend or to atendency to more easily define their experience as bully-ing. About the perception of harassment, women mainlyfocus on criticisms and rumors about their private...

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