... μg/L
penicillin in a humidified incubator containing 5% CO
2
at 37°C. The immortalized esophageal cell line NE-3
was obtained from Dr. Jin (the University of Hong
Kong, P. R. China)[26] and cultured in ... mitotic kinase CDK1/cyclin B complex in
the cytoplasm to stimulate cell cycle progression [16].
Furthermore, overexpression of CDC25B has been
observed in a variety of human cance...
... results of the VAS
rating and the absence of dropouts associated to intoler-
ance to treatment. The increase in the motor FIM™
and the decrease on the VAS for the pain might be du e
to different strategies ... were not included in the
study: (a) patients with severe cognitive, linguistic or per-
ceptive impairment (Mini Mental State Examination
(MMSE) < 24); (b) patients wh...
... Response
Integrin Signaling
VEGF Signaling
Fcγ Receptor-mediated Phagocytosis in MPs
Neurotrophin/TRK Signaling
p53 Signaling
PTEN Signaling
IL-6 Signaling
PI3K/AKT Signaling
Erythropoietin Signaling
Clatrin-mediated ... citation purposes)
or internal cellular sequestration of their receptors in
hematopoietic cells, an inability of the receptor to bind
the factor normally, or to incre...
... cells with wild -type BRAF, in which
RAF1 is activated (reviewed in [ 6]). We showed that in
BRAF wild -type melanoma cells, PLX4032 stimulated the
downstream intracellular signaling pathway, causing ... mutations. Our
preclinical data demonstrating s imilar kinase activity of
the V600K and V600E mutations, together with clear
evidence of clinical activity of PLX4032 in a patien...
... 0.01) domains of the CRQ, and
in the Symptom scores (OR = 2.11, p = 0.01) in the SGRQ.
Only the SGRQ Symptom scores with worse baseline
scores showed a significant influence on the decline in
health ... self-administered at base-
line, and again after 6 months under the supervision of
the investigators, in the same order, in booklet form. An
investigator (T.O.) reviewed the survey...
... instru-
ments are sensitive enough to detect differences that are
clinically important, they remain valuable tools for eval-
uating clinical outcomes and mea sure disease burden,
especially in ... have
been developed [5]. Using these items the ceiling and
floor effects common with most health measuring
instruments can be minimized. We concur with Ian
McDowell that in the future thes...
... determi-
nants: monthly income level of parents and assigned hos-
pital class during the diagnostic process. Both
determinants are obtained routinely during admission to
the clinic and recorded in the medical ... (corresponding to 100, 50, 0).
For this age, a Face Scale was used, comprising of 3 pic-
tures of facial expressions varying from a smiling face to a
very sad face to indic...
... promoting
compensational strategies, in order to increase the level
of independence. During rehabilitation training move-
ments are practiced preferably with high intensity, in a
task-oriented way, with an active ... 1988.
25. Levin MF: Interjoint coordination during pointing movements is
disrupted in spastic hemiparesis. Brain 1996, 119(Pt 1):281-293.
26. Sukal TM, Ellis MD, Dewa...
... has
been shown to be the predictor of morbidity and mor-
tality in CKD 3-5 patients in Spain (31). Our study ex-
tends this finding to patients with more preserved
renal function in American population. ...
oxidative stress in patients with CKD. In order to re-
duce cardiovascular mortality, nutritional,
anti-inflammatory and antioxidant intervention will
need...
... predictors and classify them according to Little and Rubin ("missing
completely at random”, “missing at random” and “missing not at random”).
Results: The type of missingness was missing at ... gentle
introduction to imputation of missing values. Journal of Clinical
Epidemiology 2006, 59:1087-1091.
24. Simes JR, Greatorex V, Gebski VJ: Practictal approaches to minimize
problems...