... demonstrable seasonal variations,population variations, and a mechanism of action.To make sense of influenza's epidemiology, we reviseHope-Simpson theory, hypothesizing marked variation in the infectivity ... Nations Health 1951,41(7):796-805.64. Kingston D, Lidwell OM, Williams RE: The epidemiology of the common cold. III. The effect of ventilation, air disinfectionand room size. J Hyg (London) ... our revision of Edgar Hope-Simpson'stheory has profound implications for the prevention of influenza.IntroductionIt is useful, at times, to question our assumptions. Argua-bly, the most...