báo cáo hóa học: " Interferon regulatory factor 3 plays an anti-inflammatory role in microglia by activating the PI3K/Akt pathway" doc

... contributing to 1 Interferon regulatory factor 3 plays an anti-inflammatory role in microglia by activating the PI3K/Akt pathway Leonid Tarassishin*, Hyeon-Sook Suh, and Sunhee ... versions will be made available soon. Interferon regulatory factor 3 plays an anti-inflammatory role in microglia by activating the PI3K/Akt pathwayJournal of Neuroinflammation 2011, 8:187 doi:10.1186/1742-2094-8-187Leonid ... required PI3K/Akt. Conclusions: Our results show a novel anti-inflammatory role for the PI3K/Akt signaling pathway in microglia. They further suggest that IRF3 gene therapy could facilitate the microglial...

báo cáo hóa học: " Interferon regulatory factor-7 modulates experimental autoimmune encephalomyelitis in mice" docx

... KH: Interleukin-1 and IL- 23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity. Immunity 2009, 31 :33 1 -34 1. 48. Kristjansdottir G, Sandling JK, ... Honda K, Takaoka A, Taniguchi T: Type I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors. Immunity 2006, 25 :34 9 -36 0. 23. Brod SA, Scott ... euthanized 4 mice was 3- 4, and all other euthanized mice had clinical score 5. At the end of experiment all remaining mice were euthanized. In the second and third experiment, half of the...

báo cáo hóa học: " Tumor necrosis factor-mediated inhibition of interleukin-18 in the brain: a clinical and experimental study in head-injured patients and in a murine model of closed head injury." pot

... G: Induction of the pro-inflammatorycytokine interleukin-18 by axonal injury. J Neurosci Res 2001,65 :33 2 -33 9.9. Yatsiv I, Morganti-Kossmann MC, Perez D, Dinarello CA, Novick D,Rubinstein ... production in murine brains within 24hours. In contrast, the intracerebral injection of murineIntracerebral IL-18 concentrations in mice, as determined by ELISA in murine brain homogenates (n = 10 animals ... pro-inflammatorymediators, depending on the kinetic of their expressionand posttraumatic regulation in the injured brain [3, 12, 13] . However, the TNF-dependent regulation of IL-18 in the injured...

báo cáo hóa học: " Hypoxia-inducible factor-1 (HIF-1) is involved in the regulation of hypoxia-stimulated expression of monocyte chemoattractant protein-1 (MCP-1/CCL2) and MCP-5 (Ccl12) in astrocytes" pdf

... the transmigration ofmonocytes and macrophages across the BBB to the sites ofaxonal injury in the brain [33 ,37 ]. Both in vitro and in vivofindings suggest that hypoxia/ischemia-induced infiltra-tion ... an important role in the initiation and propagation of hypoxia/ischemia-induced inflammation by secretinginflammatory chemokines that attract neutrophils and monocytes into the brain. However, ... of inflammatory cells in focal brain ischemiaof hypertensive rats [38 ]. Astrocytes are main cytokine/chemokine-producing cells in the brain [34 ,37 ], andastrocyte-produced MCP-1 directs the...

báo cáo hóa học:" Function of anterior talofibular and calcaneofibular ligaments during in-vivo motion of the ankle joint complex" docx

... during the flexion-extension arc of motion. Theydemonstrated increased strain in the ATFL with increasingplantarflexion, inversion and internal rotation. Strain in the CFL was found to increase ... complaints of ankle pain, previoushistory of ankle injury requiring treatment, systemic dis-ease, or contraindication for MR imaging. Prior to MRscanning, both ankles, including the scanned and ... 20cadaveric ankles. In their study, the average ATFL lengthwas 17.8 ± 3. 1 mm and the average CFL length was 27.7 ± 3. 3 mm. Burks and Morgan also measured the length oflateral ankle ligaments in their...

Báo cáo hóa học: " Genetic diversity and silencing suppression effects of Rice yellow mottle virus and the P1 protein" doc

... Isoleu-cine, N19I) and phenylalanine 88 (Phenylalaninechanged by Tyrosine, F88Y). The efficacy of these mutantsto abolish silencing of the uidA transgene in L10 wastested following biolistic ... beadapted to balance the viral effect (i.e. pathogenicity) in the host, while limiting viral-induced host gene silencing in order to preserve the integrity of the plant machineryduring the infection ... illustrated by isolates belonging to the same serotype Ni2 and CI4, or, CI 63 and BF1 isolates(Figure 3C, lanes 3 and 4 or 4 and 5). We also noted that the diversity of silencing suppression displayed by...

báo cáo hóa học:" Radiolabeling, biodistribution and gamma scintigraphy of noscapine hydrochloride in normal and polycystic ovary induced rats" doc

... ascer-tain whether noscapine can be used in the diagnosis ofdeveloping tumors, including those inflicting the ovaries.We were therefore interested in exploring the possibilityof using nuclear ... macro- and microplanning,result analysis, and writing the paper. All authors participated in the discussionand interpretation of the final results, contributed to the final paper, andapproved the ... MI, Javanmardi SZ, Mahmoudian M, et al.: Noscapine suppresses angiotensin converting enzyme inhibitors-induced cough. Nephrology (Carlton) 2005, 10 :34 8 -35 0. 33 . Aneja A, Dhiman N, Idnani J,...

Báo cáo hóa học: " Research Article Strong Convergence of an Implicit Algorithm in CAT(0) Spaces" pdf

... between any two points of X is taken tobe the in mum of the lengths of all rectiﬁable paths joining them. In this case, d is said to bea length metric otherwise known as an inner metric or intrinsic ... Guo, and Y. J. Cho, “Some general convergence principles withapplications,” Bulletin of the Korean Mathematical Society, vol. 40, no. 3, pp. 35 1 36 3, 20 03. 7 H. Fukhar-ud-din and A. R. Khan, ... Pakistan2Department of Mathematics, Taibah University, Madinah Munawarah 30 002, Saudi Arabia 3 Department of Mathematics and Statistics, King Fahd University of Petroleum and Minerals,Dhahran 31 261,...

Báo cáo hóa học: " Research Article Outage Probability versus Fairness Trade-off in Opportunistic Relay Selection with Outdated CSI" doc

... distance, dA,Bis the distanceof the link A-B,andμ is the path-loss coeﬃcient (being μ= 3 in this work). We assume a block-fading channel where the channel response remains constant during ... message to the destination(i.e., BS) indicating that they are able to relay the message. This signalling message can be, for instance,a pilot sequence used by the BS to estimate the instantaneous ... considering the inclusion of cooperative techniques in practical systems. For instance, the IEEE 802.16j Relay TaskGroup [6] is involved in the incorporation of relayingmechanisms in the standard...

Báo cáo hóa học: "Research Article Strong Convergence of an Iterative Method for Equilibrium Problems and Variational Inequality Problems" docx

... 2αnM1, 3. 32hence from conditions i, iii,and 3. 26, we havelimn →∞Ayn− Ap 0. 3. 33 Similarly, submitting 3. 29 into 3. 30, we also havelimn →∞Aun− Ap 0. 3. 34Step ... K2, 3. 21Fixed Point Theory and Applications 2112 W. Takahashi and M. Toyoda, “Weak convergence theorems for nonexpansive mappings andmonotone mappings,” Journal of Optimization Theory and ... 2, pp. 417–428,20 03.  13 H. Iiduka and W. Takahashi, “Strong convergence theorems for nonexpansive mappings and inverse-strongly monotone mappings,” Nonlinear Analysis: Theory, Methods &...

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