... response to western-type diet. Specifically, we found
that apolipoprotein E3 knock -in mice fed western-type diet for 24 weeks
became obese and developed hyperglycemia, hyperinsulinemia, hyperleptin-
emia, ... the 24-week period of feeding mice with
western-type diet, fasting plasma samples were taken
every 6 weeks, and cholesterol, triglyceride and free
fatty acid levels were...
... Authors Journal compilation ª 2007 FEBS
Apolipoprotein E-derived antimicrobial peptide analogues
with altered membrane affinity and increased potency and
breadth of activity
Bridie A. Kelly
1
, Stuart ... the
contribution of individual residues, and show that sub-
stitutions for aromatic residues increase potency and
breadth of activity, giving rise...
... Access
Research
Three-dimensional growth as multicellular spheroid activates the
proangiogenic phenotype of colorectal carcinoma cells via
LFA-1-dependent VEGF: implications on hepatic micrometastasis
María ...
hour
of incubation of monolayer- and 3D -spheroid- cultured
CT26 cells. For both culture conditions, the concentration
of VEGF was expre...
... mitotic kinase Aurora- A
to be overexpressed in ovarian carcinomas compared to
adenomas. Furthermore, we demonstrated the pan-
Aurora inhibitor VE-465 can synergize with paclitaxel to
induce apoptosis ... purposes)
Journal of Translational Medicine
Open Access
Research
Aurora kinase inhibitors synergize with paclitaxel to induce
apoptosis in ovari...
... preprocessing of data that included averaging of tech-
nical repeats, interpolation of missing or non-aligned
points, binning of neighboring points to reduce data com-
plexity, removal of the spectral ... resolu-
tion of the analyzer operating in the linear mode or might
result in overlapping of ions originating from protein/
peptides of very similar molecular masses. I...
...
upon the risk of mother-to-child transmission (MTCT) of Human Immunodeficiency Virus type 1 (HIV-1). The aim of this
study was to investigate the influence of genetic variants of TLR 9 gene on MTCT.
Methods: ... original work is properly cited.
Research
Toll-like receptor 9 polymorphisms influence
mother-to-child transmission of human
immunodefic...
... using semi-nested primers. The primer set
BG1 (TATGGTGGGAGAAGAAATTAGTAAAGG) and
BG2 (AATAACCTTATCCTCCTCTATAAAATAACC)
were used in the first round and BG2 and BG5
(GGTTGGTTAGTTTTGTTTTGATTAATAG) ... Open Access
S110, a novel decitabine dinucleotide, increases
fetal hemoglobin levels in baboons (P. anubis)
Donald Lavelle
1,2*
, Yogen Saunthararajah
1,3
, Kestis Vaitku...
... Access
Treatment combining RU486 and Ad5IL-12 vector
attenuates the growth of experimentally formed
prostate tumors and induces changes in the
sentinel lymph nodes of mice
Claudia Raja Gabaglia
1
, Alexandra ... combining RU486 and
Ad5IL-12 vector attenuates the growth of experimentally formed
prostate tumors and induc...
... Pharmacol Sin 2006, 27:1153-1158.
doi:10.1186/1479-5876-9-11
Cite this article as: Leu et al.: Myocardium-derived conditioned medium
improves left ventricular function in rodent acute myocardial infarction.
Journal ... Medicine 2011, 9:11
http://www.translational-medicine.com/content/9/1/11
Page 18 of 18
RESEARCH Open Access
Myocardium-derived conditioned medium
i...
... the three TR APOE mice. Recovery of dendrite length over the next 48 hr was greater in TR APOE2 than
TR APOE3 mice, while TR APOE4 mice had failure of dendrite regeneration. Cell culture experiments ... demonstrated
that despite brain regional differences in apoE expression,
there are no isoform-specific differences in levels of apoE
in brain tissue from these TR APOE mice, even with...
... cytokines is elevated, the expression of IL -1- driven AD-related proteins such as
ApoE would be elevated as well. Multiple MLKs—ERK, p38-MAPK, and JNK—were shown to
be involved in elevated expression ... made available soon.
Apolipoprotein E expression is elevated by interleukin 1 and other interleukin
1- induced factors
Journal of Neuroinflammation 2 01...
... of 9
(page number not for citation purposes)
Virology Journal
Open Access
Research
Kaposi's sarcoma associated herpesvirus G-protein coupled
receptor activation of cyclooxygenase-2 in vascular ... vGPCR induces COX-2
expression in primary vascular endothelial cells and may
be responsible for the COX-2 and PGE
2
increases observed
following infection in mi...
... hypothesized to involve other mechanisms such as twitching. This
idea was reinforced by the findings [8] that inside the spine, the cytoplasmic actin is
organized in filaments, involved in various forms ... model of protein trafficking in spines. Biophys.
J. 96, 1786–1802 (2009)
57. Bressloff, P.C.: Cable theory of protein receptor trafficking in dendritic trees. Phys. Rev. E, Stat.
Non...
... NMDA-spikes
can arise in certain dendritic zones. In the context of reinforcement learning, two
kinds of plasticity rules are derived, zone reinforcement (ZR) and cell reinforcement
(CR), which ... second integration extending from time t into the
future up to t + ∆. The acausality of integrating into the future can be taken
care of by time shifting the integration variable in t...