... administration of ibuprofen can reduce
plaque pathology and brain Aβ levels in these animal
models of AD [8,9].
There are numerous reports of increased levels of
cytokines in the brains of Alzheimer's ... Acosta-
Martinez JP, Ortiz GG: Kinetics of the neuroinflammation-oxi-
Additional File 1
Correlation table of levels of different
β
-amyloid species with...
... by
incubating the sections in 1% thioflavine for 30 minutes
followed by a 1 minute wash in 50% ethanol, 5 min in
deionized distilled water, and 5 min in PBS. Sections incu-
bated in parallel without ... immunized with oligo
Aβ. C3 staining in animals immunized at 16–20 months
correlated with thioflavine staining with no increase or
decrease in C3 deposition detectable in...
... TP508 was tested in a
mouse model mimicking high energy-fracture conditions
with soft tissue injuries, and showed positive effects on
enhancing fracture healing. The time to union in mouse
A-C. Histological ... fracture gap. This is in agreement with pre-
vious studies showing the benefit of TP508 in enhancing
healing of various musculoskeletal tissues [8,9]. The
group rec...
... originating from East-Africa or
Comoros was introduced into India in 2006 (fig-1&2). In
2007, an infected traveller from India arrived in Italy and
caused more than 200 indigenous cases of ... observed in nature. In virol-
ogy, convergent mutations have been reported under the
extreme selective pressure of antiviral therapy during the
treatment of acute (eg neuraminidase m...
... prevalence
of insulin resistance and type 2 diabetes [9], which may
increase long term morbidit y among those with PCOS.
Recent research indicated higher insulin concentrations
and lower insulin sensitivity ... pre-existing differences in
HRQoL of the groups investigated. Only one study to
date has measured the HRQoL of a sample of Indian
women with PCOS and found high prevalenc...
... al. [11], for
instance, found a rate of disagreement in a population of adolescents with juvenile
idiopathic arthritis (JIA) that is consistent with our findings, while Ylimainen et al.
[31] ... provides a singular index
of global HRQoL [21, 24]. Its 10 items are all scored on a 5-point scale ranging from
‘never/not at all’ to ‘always’. The item scores are combined into a fina...
... fracture fixing often
causes infection and reduced skeletal load resulting in implant failure. Creating new wires with drug-eluting
properties to locally deliver drugs is an appealing approach ... loaded into
nanotubes all around the wire. Loading, drying and wip-
ing steps were repeated 20 times in order to load a sub-
stantial amount of drug into the nanotubes.
Quantitative anal...
... quickly changing and verifying the communication network topology if compared with
hardware prototypes.
1. Introduction
The amount of electronics used in vehicle systems is growing
fast with the ... 854–857,
Seville, Spain, August 2007.
[11] J. Chew and C. Sullivan, “Verification, validation, and accred-
itation in the life cycle of models and simulations,” in
Proceedings of...
... heavy chain protein is consistently recoverable from IgG-
expressing plants. Again this is consistent with the model for
BiP in assisting protein folding and increasing throughput of
the ER. In mammals, ... versatility of
transgenic plants for producing a variety of mammalian
proteins. Protein translocation and folding in the ER can
be one of the rate limiting steps in pro...