Báo cáo sinh học: " Influence of helium-ion bombardment on the optical properties of ZnO nanorods/p-GaN light emitting diodes" pot
Báo cáo Y học: Kinetic and biochemical analyses on the reaction mechanism of a bacterial ATP-citrate lyase ppt
... Anotherfunction of AclB was found to be stabilization of the enzyme, as AclB prevented the degradation of AclA thatwas otherwise observed in the absence of AclB.After the phosphorylation, ... mechanism of mammalian ACL [23], the final step of the reaction can be assumed to be the nucleophilic attack of CoA to the phosphorylated carbonyl carbon of citrylphosphate, and the cleavage of the ... 4½S3=a2bK3Sþ½S4=a3b2cK4SÞwhere v is the initial velocity of the reaction, Vmaxis the maximum velocity, [S] is the concentration of citrate, Ksis the dissociation constant of the enzyme-citrate (ES) com-plex,...
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Báo cáo khoa học: Temperature and salts effects on the peptidase activities of the recombinant metallooligopeptidases neurolysin and thimet oligopeptidase pdf
... [3]; and from the deconvolution of CD at 37 °C in the absence of NaCl (195–260 nm) was 51%. For the spectrum of TOP in the sameconditions the deconvolution indicated 45% of a helixcontent. This ... Val position in order to verify the influence of the nature of the amino acid at this position on determination of the cleavage sites and on the amount of their hydrolysis. This series of peptides ... and the variations of the cleavage sites wereevaluated under different conditions of temperature andsalt concentration. The relative amount of cleavage variedwith the nature of the substitution...
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Báo cáo y học: "PKC and PKA Phosphorylation Affect the Subcellular Localization of Claudin-1 in Melanoma Cells"
... render the potential sites of PKC and PKA phosphorylation on the claudin-1 pro-tein non phosphorylatable or to mimic constitutive activation of PKC or PKA. B) Rendering the serine at position ... mutating the PKC phosphorylation sites to mimic a non-phosphorylated state did not cause a shift of claudin-1 to the nucleus of the cells, but mutating the PKA sites did. Mutations of either site ... was used at a concentration of 10μM for the indicated times. The PKA activator, forskolin (Sigma) was used at a concentration of 5 μM for the indicated times. Immunofluorescenct confocal microscopy....
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Tài liệu Báo cáo khoa học: Toggle switches, pulses and oscillations are intrinsic properties of the Src activation/deactivation cycle doc
... modu-lation of Ca2+oscillations by increasing agonist con-centration [44]. The dependences of the period of oscillations on the RPTP and Csk concentrationsalmost mirror each other, although there ... from the Offstate to On state (in the bistability domain). Regardless of the slope, the active Src fractions increase during the Off to On transition, whereas the value of the inac-tive fraction ... thatmirror stimulation or changes in the external condi-tions.We consider the time scale on which the total Srcconcentration (Stot) is conserved. Neglecting the con-centrations of dimers, S Á...
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Tài liệu Báo cáo khoa học: Ionic strength and magnesium affect the specificity of Escherichia coli and human 8-oxoguanine-DNA glycosylases pdf
... is the case for almost allDNA glycosylases [47], the preferences for each sub-strate may depend on the reaction conditions to differ-ent degrees. The influence of the reaction conditions on ... toinduce conformational transitions in nucleic acids, pos-sibly by selective stabilization ⁄ destabilization of one of the conformations; for example, submillimolar concen-trations of Mg2+induce ... USA).Kinetic constant determination The reaction mixtures were as in the standard assay, exceptthat the components specified in the Results were added, and the concentrations of the substrate...
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Tài liệu Báo cáo khoa học: "Enhanced word decomposition by calibrating the decision threshold of probabilistic models and using a model ensemble" pdf
... ap-proaches is based on the learning aspect during the construction of the morphological model. If the data for training the model has the same struc-ture as the desired output of the morphologicalanalysis, ... independently from other boundaries (zero-order) and the graphemic representation of the word, however, is conditioned on the length of the word mjwhich means that the probabilitydistribution is in ... Interna-tional Conference on Machine Learning, Pittsburgh,PA, 233–240.M. Gasser. 1994. Modularity in a connectionistmodel of morphology acquisition. Proceedings of the 15th conference on Computational...
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Tài liệu Báo cáo Y học: Electrochemical, FT-IR and UV/VIS spectroscopic properties of the caa3 oxidase from T. thermophilus docx
... presented and on this basis the contributions of the reorganization of the polypeptide backbone, of individual amino acids and of the hemes c, a and a3upon electron transfer to/from the redoxactive ... to the different environ-ment of the heme centers. The difference signals observed at442 nm and 603 nm can be assigned to the contributions of the hemes a and a3, with the position of the ... spectra of isolatedamino acids as model compounds and information on contributions from the secondary structure from infraredabsorbance spectra and the deconvolution of the amide-Iregion.A...
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Báo cáo khoa học: Nanoparticles can induce changes in the intracellular metabolism of lipids without compromising cellular viability docx
... However, the mechanisms involved in the down-regulation of fatoxidation by NPs require further investigation.Fat accumulation and the down-regulation of the b-oxidation of FFAs were induced in PC12 ... that the degree of inter-nalization of QDs and various other NPs is dependent on their size, surface charge, concentration in the med-ium and duration of exposure [4,7–11]. We have alsoshown the ... aswell as the hypoxia mimetic CoCl2, induced the up-regulation of hypoxia-inducible transcription factor-1a and the down-regulation of the b-oxida-tion of fatty acids, both of which could contribute...
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Báo cáo khoa học: C fi G base mutations in the CArG box of c-fos serum response element alter its bending flexibility Consequences for core-SRF recognition potx
... dependstrongly on the temperature [53,54]. Indeed, the changein the array of the hydrogen bonds at thymine of SREGGfosis probably a sign of perturbation in the hydration scheme along the minor ... information on the localrepartition of the angles involved in the SREfoshelixbending.Relative effect of bending strainThere are several indications of a redistribution of the strains exerted on ... ⁄ +5 of the CArG box are highly con-served [19]. In the case of SREGfos, the G–C base pairinversion at )5 position precludes formation of the hydrogen bond between the K163 residue of the core-SRF...
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Báo cáo khoa học: Structural and thermodynamic insights into the binding mode of five novel inhibitors of lumazine synthase from Mycobacterium tuberculosis pptx
... in the position of the pyrimidine ring, whereas the phos-phate and phosphonate moieties occupy the same posi-tion in spite of the different conformation of the alkylchain. The positions of the ... inhibitors. The centre of the pyrimidine moi-ety is located in a position which corresponds to the position of the common bond between the two rings in the purinetrione system (Fig. 3) in complexes of MbtLS ... from their parallel ring positions. The shiftedposition of the pyrimidine system, together with the small size of this group causes different interactions of the carbonyl oxygen atoms of the...
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Từ khóa: Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngchuyên đề điện xoay chiều theo dạngNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpNghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt namBiện pháp quản lý hoạt động dạy hát xoan trong trường trung học cơ sở huyện lâm thao, phú thọGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhĐịnh tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Tổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Kiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Tăng trưởng tín dụng hộ sản xuất nông nghiệp tại Ngân hàng Nông nghiệp và Phát triển nông thôn Việt Nam chi nhánh tỉnh Bắc Giang (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtBÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIĐổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namMÔN TRUYỀN THÔNG MARKETING TÍCH HỢP