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Báo cáo sinh học: "Safety and feasibility of third-party multipotent adult progenitor cells for immunomodulation therapy after liver transplantation–a phase I study (MISOT-I)" doc

Báo cáo sinh học:

Báo cáo sinh học: "Safety and feasibility of third-party multipotent adult progenitor cells for immunomodulation therapy after liver transplantation–a phase I study (MISOT-I)" doc

... AccessSafety and feasibility of third-party multipotent adult progenitor cells for immunomodulation therapy after liver transplantation–a phase I study (MISOT -I) Felix C Popp1†, Barbara Fillenberg1†, ... the eligibility criteria given inFigure 3. All suitable patients will be informed about the study during a regular outpatient visit and asked for their willingness to partici pate. Specific study ... feasibility of third-party multipotent adult progenitor cells for immunomodulation therapy after liver transplantation–a phase I study (MISOT -I) . Journal of TranslationalMedicine 2011 9:124.Submit your...
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Báo cáo sinh học: "Safety and pharmacokinetics of recombinant human hepatocyte growth factor (rh-HGF) in patients with fulminant hepatitis: a phase I/II clinical trial, following preclinical studies to ensure safety" ppt

... I/ II clinical trial of rh-HGF. As this application isthe first clinical trial to a dminister rh-HGF to humans,we performed additional preclinical studies to ensureminimization of the predicted ... clinical efficacy. Therefore, it will bedesirable to examine the clinical efficacy of rh-HGF inadditional clinical trials involving patients with lesssevere conditions.Systemic administration ... 14) and the obser-vation period (day 28) to evaluate renal involvement,including serum creatinine and histological findings.A phase I/ II clinical trial for patients with acute liver failureOverviewThis...
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Báo cáo sinh học: " Transcription and translation of human F11R gene are required for an initial step of atherogenesis induced by inflammatory cytokines" doc

... the initiation of a therogenesis.This study demonstrates that inhibition b y specificsiRNA of the de-novo biosynthesis of F11R, induced inendot helial cells by inflammatory cytokines, significantly50 ... indicates the level of significance determined at a specific interval of time of cytokine- treatment of ECs in comparison to the zerotime points.Azari et al. Journal of Translational Medicine ... progression of this chain of events by the use of two blockers of mRNA synthesis:Actinomycin, an overall inhibitor of RNA synthesis, and F11R-siRNA, a specific inhibitor of the synthesis of F11R-mRNA....
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Báo cáo y học:

Báo cáo y học: " Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial"

... 20/26 (76.9%) Discussion OA is the most common form of arthritis, and it is often associated with significant disability and an impaired quality of life. Clinical and radiographic surveys have ... receiving placebo did not show any improvement in arthritic condition, while those re-ceiving a daily dose of 320, 480 or 640 mg of UC-II exhibited significant reduction in arthritic pain. ... ibuprofen within 7 days of randomization Subject is unwilling to stop taking pain medication other than the study medication (for arthritis or other types of pain) or is unwilling to stop taking other...
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báo cáo sinh học:" Burnout and use of HIV services among health care workers in Lusaka District, Zambia: a cross-sectional study" pot

... Board.ResultsIn May 2007, 78 individuals were invited for focus groupdiscussions. Fifty (64%) participated: 18 nurses, eightmidwives, nine clinical officers, five medical officers and 10 pharmacy ... provided written informed consent to par-ticipate. This study was approved by the University of Zambia Research Ethics Committee and the University of Alabama at Birmingham Institutional Review ... centres).Participants in both study components conveyed worryover accidental disclosure of HIV infection. Ironically, thisfear of disclosure has made utilization of HIV servicesmore difficult for these ministry...
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Báo cáo sinh học: " Attenuation and efficacy of human parainfluenza virus type 1 (HPIV1) vaccine candidates containing stabilized mutations in the P/C and L genes" potx

... level of replica-tion of vaccine virus and its immunogenicity and abilityto restrict replication of HPIV1 challenge virus. Theseresults can be interpreted to indicate that the two vaccinecandidates ... in AGMs by measuring post-immunization HPIV1 hemagglutination inhibiting (HAI)serum antibody titers and by challenging immunized and control animals with HPIV1 wt 28 days following immu-nization ... recovered viruses, performed in vitro and in vivo stud-ies and drafted the manuscript. AC recovered virus and performed in vitro and in vivo studies. SRS recoveredviruses and assisted with in vivo...
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Báo cáo sinh học: " Detection and frequency of recombination in tomato-infecting begomoviruses of South and Southeast Asia" pptx

... documented in this study would provide new information for understanding thediversity and evolution of tomato-infecting begomovi-ruses in Asia. In addition to evolutionary considerations,understanding ... India.In addition, we provide evidence for non-random distribution of recombination events with thehighest frequency of recombination being mapped in the portion of the N-terminal portion of ... frequencies of phylogeny viola-tions for each pairwise comparison of sequence fragmentsFigure 3Phylogenetic compatibility matrix of tomato-infecting bego-movirus sequences, exhibiting frequencies of...
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Báo cáo sinh học: " Construction and characterization of recombinant flaviviruses bearing insertions between E and NS1 genes" docx

... attenuated and used for human vaccination for 70 years. Some of the outstandingproperties of this vaccine include limited viral replicationin the host but with significant expansion and dissemina-tion ... Differences in the titers of neutralizing antibodies virus in animals immunized with YF 17DD and YF17D/Esa/5.1glic were statistically significant (t test; P < 0.02).***The titer of antibodies directed ... capable of eliciting significant titers of neutralizing antibodies to YF.All animals seroconverted to YF virus after subcutaneousinoculation with either virus. For YF17D/Esa/5.1glic virusthe antibody...
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Báo cáo sinh học: "Construction and characterization of an infectious clone of coxsackievirus A16" docx

... obtained using the primer pairs P3/P4 and P5/P6 (Table 1), respectively. CV(1–4392) and CV(4381–7410) were digested with HindIII/XbaI and XbaI/NotI, respectively, and ligated into HindIII/NotI ... digested with NotI, purified and used as the template for in vitro transcription. In vitro transcription was performed using the Riboprobe system-T7 in vitro transcription kit (Promega, Madison, ... negative strands used to demonstrate specificity of positive-strand encapsidation and the ratio of positive to negative strands in infected cells. J Virol 1991, 65:3384–3387. 31. Giachetti C,...
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Báo cáo sinh học: " Development and implementation of explicit computerized protocols for mechanical ventilation in children" pot

... a decision at the bedside in a specific situation and thus significant inter-clinician variability in their application may exist. An explicit protocol is designed to provide enough details ... to generate patient-specific therapy instructions that can be performed by different clinicians with no inter-clinician variability [8]. Important individualization of patient therapy can be ... within predefined range within predefined ranges Initial settings IBW, humidification system, IBW, medical history medical history Clinical decision support No Yes Option (open-loop) Input...
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