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báo cáo hóa học: " Relationship between the EQ-5D index and measures of clinical outcomes in selected studies of cardiovascular interventions" pot

báo cáo hóa học:

báo cáo hóa học: " Relationship between the EQ-5D index and measures of clinical outcomes in selected studies of cardiovascular interventions" pot

... 3). In general,there was a stronger relationship between CCS class and EQ-5D index in angina trials pre-treatment than in the other disease/treatment groups.For the SAQ, the EQ-5D index increased ... positive relationship with the EQ-5D index, where the EQ-5D index increased by 0.019 (95%CI 0.014, 0.025) for each minute increase in ETT (Table 3 and Figure 2). The relationship between ETT and the ... those included in cohort studies. This couldlead to less variability in the variables of interest in thesepatients, and in particular, the ceiling effect may constrain the variation in EQ-5D index...
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Báo cáo khoa học: Relationship between the structure of guanidines and N-hydroxyguanidines, their binding to inducible nitric oxide synthase (iNOS) and their iNOS-catalysed oxidation to NO pptx

Báo cáo khoa học: Relationship between the structure of guanidines and N-hydroxyguanidines, their binding to inducible nitric oxide synthase (iNOS) and their iNOS-catalysed oxidation to NO pptx

... NOHA[10], nothing is known about the thermodynamics and kinetics of the binding of guanidines and N-hydroxy-guanidines to iNOS. Removal of the a-amino ora-carboxylate moiety of l-Arg has important ... Kd and koff. The fol-lowing experiments were performed as a first approachto find the variation in koffas a function of the iNOSsubstrate structure.Kinetics of the binding of guanidines and N-hydroxyguanidines ... in the iNOSheme pocket thus roughly involves the same bindingenergy as binding of the guanidine moiety, and the equilibrium constants are mainly determined by the alkyl or aryl substituents of...
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Báo cáo sinh học:

Báo cáo sinh học: " Relationship between the loss of neutralizing antibody binding and fusion activity of the F protein of human respiratory syncytial virus" doc

... under-standing of the mechanism by which the F protein medi-ates cell fusion. Such studies may provide additionalinsights into the function of the F protein, and help in the selection and development ... understand the mechanism of action of HRSV neutralizing antibodies and the impact of resistance to these antibodies upon the fusion activity of the F protein. A summary of these resultsis presented in ... good candidatesfor clinical development (ch101F)[20], respectively. Theyalso recognize one of the two major antigenic sites (site IIor site IV/V/VI) within the F protein, and residues in theirepitopes...
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Báo cáo y học:

Báo cáo y học: "Relationship between Anti-CCP Antibodies and Oxidant and Anti-Oxidant Activity in Patients with Rheumatoid Arthrit"

... in RA patients. Anti-CCP antibodies are directed against antigens containing the nonstandard amino acid citrulline, for example, citrullinated fibrin, which is found in the rheumatoid joint ... rheumatoid joint [21]. The citrulline moiety, which is the essential part of the antigenic determinant in these antigens, is post-translationally generated by peptidyl arginine deiminases (PAD) [22]. ... (H2O2), and hydroxyl rad-ical (OHS), with the potential to initiate cellular damage in joint tissues especially in RA. They are formed by phagocyte activation during inflammation. The current...
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báo cáo hóa học:

báo cáo hóa học: " Associations between general self-efficacy and health-related quality of life among 12-13-year-old school children: a cross-sectional survey" potx

... parents and children were returned to the teachers. The schoolnurse assisted in the information gathering process and in the data collection tasks. The self-report instruments werecompleted in the ... with gender in analyses of rela-tionships between GSE and HRQOL, an interaction termwas included in the statistical model.According to the manual, the missing values of HRQOL and GSE were ... other schools selected according to the same criteria. Children in sev-enth grade in the selected schools with sufficient compe-tence in the Norwegian language were included in the study.The...
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Báo cáo hóa học:

Báo cáo hóa học: " Associations between disease severity, coping and dimensions of health-related quality of life in patients admitted for elective coronary angiography – a cross sectional study" pdf

... analysis and in drafting the manuscript, ON coordinated the study at the hospital and participated in data collection, and in drafting the manuscript, BRH and AKW participated in planning and designing ... to an aging population of cardiacpatients, therapeutic efforts also increasingly focus onimproving patients functioning and wellbeing. Therefore,identification and understanding the relationships between ... analysesNonlinearity was indicated for LVEF and body mass index and for General Health at level 6. All other continuousindependent variables were entered linearly into the mod-els. The results for the...
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Báo cáo khoa học: Relationship between functional activity and protein stability in the presence of all classes of stabilizing osmolytes ppt

Báo cáo khoa học: Relationship between functional activity and protein stability in the presence of all classes of stabilizing osmolytes ppt

... advances in understanding the effect of osmolytes on protein stability, folding and the activity of proteins and enzymes, the relationship between protein stabilization by osmolytes and its con-sequent ... [21–25], and DGD° values in the presence of these osmolytes are given in Table 1. How-ever, DGD° values of RNase-A in the presence of alanine, serine, lysine, b-alanine, taurine and dimethyl-glycine ... hydration of the protein domain is the driving force of protein stabiliza-tion or folding [3,4]. Furthermore, the effect of osmolytes on the functional activity of an enzyme hasalso been investigated...
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Báo cáo y học:

Báo cáo y học: " Relationship between anal symptoms and anal findings"

... or the upright standing-bented) is the most reliable for determining the causes of anal bleeding, anal itch, anal pain or anal burning. The sensitivity, specificity and predictive value of ... Sims’ position, as the buttocks fall to each side, and finger tips of both hands of the investigator are free for gentle eversion of the anal skin with the help of a good lighting [5,14]. A fundamental ... positioning in diag-nosis of BAD, concomitant anal findings (CAF), and multiple anal lesions (MAL) with one individual also remain unknown [3,14,15]. We investigated the types and frequencies of...
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Báo cáo khoa học: Relationships between the ethanol utilization (alc ) pathway and unrelated catabolic pathways in Aspergillus nidulans pptx

Báo cáo khoa học: Relationships between the ethanol utilization (alc ) pathway and unrelated catabolic pathways in Aspergillus nidulans pptx

... sufficient to produce and maintain an inducing quantity of acetaldehyde in the presence of ethylacetate. Induction of the alc system in analcA-independent manner could be explained presumingthat acetaldehyde ... pathway-specific induction of the aldA gene in the absence of ADHI-activity, a single, functional copy of the alcR gene was introduced into anL-arginine-auxotrophargB2 alc500 double mutant strain by ... neutralized as an inducer in the presence of these primary amines, suggesting that Schiffbase interactions between aldehydes and primary aminesoccur in vivo. The formation of a Schiff base is...
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Báo cáo Y học: Interactions between the Fyn SH3-domain and adaptor protein Cbp/PAG derived ligands, effects on kinase activity and affinity docx

Báo cáo Y học: Interactions between the Fyn SH3-domain and adaptor protein Cbp/PAG derived ligands, effects on kinase activity and affinity docx

... loops linking the individual b strands together (the RT loop, the n-Src loop, and the 310helix as indicated in Fig. 1C), flanked by strands b4 and b5. The variableloops n-Src and RT are principal ... hydrophobic and electrostaticinteractions involved in formation of the complex. The model showed peptide residues Pro4 and Pro7 fittingwell into binding grooves 1 and 2 created by the n-Srcloop and the ... stacking interac-tions of the pyrrolidine ring of Pro7 with the aromaticside chain of Tyr137. Modelling of the PRD1-superpeptide, which included two amino acid substitutions(Glu2Pro and Pro8Arg),...
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