Báo cáo sinh học: " Functional relevance of nonsynonymous mutations in the HIV-1 tat gene within an epidemiologically-linked transmission cohort" pot

Báo cáo sinh học: " Functional relevance of nonsynonymous mutations in the HIV-1 tat gene within an epidemiologically-linked transmission cohort" pot

Báo cáo sinh học: " Functional relevance of nonsynonymous mutations in the HIV-1 tat gene within an epidemiologically-linked transmission cohort" pot

... selection of multiple nonsynonymous mutations in tat in a unique epidemiologically-linked cohort following transmission of HIV-1. Comparisons of the relative transactivation abil- ities of the Tat ... and R52 participates in the binding of Tat to TAR and is involved in the nuclear local- isation of Tat [18,19]. The strong or total suppression of...
Ngày tải lên : 18/06/2014, 18:20
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Báo cáo hóa học: " Functional relevance of nonsynonymous mutations in the HIV-1 tat gene within an epidemiologically-linked transmission cohort" pot

Báo cáo hóa học: " Functional relevance of nonsynonymous mutations in the HIV-1 tat gene within an epidemiologically-linked transmission cohort" pot

... Access Short report Functional relevance of nonsynonymous mutations in the HIV-1 tat gene within an epidemiologically-linked transmission cohort Haran Sivakumaran 1,2 , Bin Wang 3 , M John Gill 4 , ... little in known about selection of mutations in the HIV-1 regulatory genes. One of the major regulatory genes of HIV-1 is tat, which encodes th...
Ngày tải lên : 20/06/2014, 01:20
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Báo cáo sinh học: "Functional characterization of human Cd33+ And Cd11b+ myeloid-derived suppressor cell subsets induced from peripheral blood mononuclear cells co-cultured with a diverse set of human tumor cell lines" docx

Báo cáo sinh học: "Functional characterization of human Cd33+ And Cd11b+ myeloid-derived suppressor cell subsets induced from peripheral blood mononuclear cells co-cultured with a diverse set of human tumor cell lines" docx

... also elevated in many of the MDSC-inducing cell lines, particularly ovar- ian and cervical cancer cell lines, and PGE 2 in combination with GM-CSF induced weak suppressive function in CD33 + cells([16],datanotshown).How- ever, ... function . These data and methods provide an important pre-clinical tool for other investigators to examine other aspects of human MDSC biology and t...
Ngày tải lên : 18/06/2014, 19:20
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Báo cáo sinh học: " Functional inaccessibility of quiescent herpes simplex virus genomes" doc

Báo cáo sinh học: " Functional inaccessibility of quiescent herpes simplex virus genomes" doc

... distinct from that exhibited by the other IE mutants in that the VP16 gene residing in the superinfecting n212 genome was efficiently expressed while the corresponding gene of KM110-R remained silent. ... by the superinfecting virus. These data suggest that the inhibitory mechanism renders many (if not all) of the cis-acting ele- ments (eg. promoters and origins of...
Ngày tải lên : 19/06/2014, 08:20
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Báo cáo khoa học: Functional expression of olfactory receptors in yeast and development of a bioassay for odorant screening docx

Báo cáo khoa học: Functional expression of olfactory receptors in yeast and development of a bioassay for odorant screening docx

... also contains a GAL4 gene under the control of the GAL10 pro- moter. The induction of the yeast, by galactose containing media, results in overexpression of GAL4, in turn inducing an increase of the ... suggests the authenticity of its ligand binding and the maintenance of the coding ability at the receptor level. Consequently this suggests that gly- cosy...
Ngày tải lên : 07/03/2014, 16:20
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Báo cáo Y học: Functional assignment of motifs conserved in b1,3-glycosyltransferases A mutagenesis study of murine UDP-galactose:b-N-acetylglucosamine b1,3-galactosyltransferase-I pptx

Báo cáo Y học: Functional assignment of motifs conserved in b1,3-glycosyltransferases A mutagenesis study of murine UDP-galactose:b-N-acetylglucosamine b1,3-galactosyltransferase-I pptx

... residues W101 and W162 are involved in the b inding of the UDP-galactose donor, t he residue W315 in the binding of the N-acetylglucosamine-b-p- nitrophenol acceptor, and the domain including E264 appears ... found in b1,3-GalTs and b1,3-N-acetylglucosaminyltransferases, thereby suggesting that they are more likely involved in mediating the b1,3-linkage speci®city r at...
Ngày tải lên : 08/03/2014, 16:20
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báo cáo sinh học:" Managerial competencies of hospital managers in South Africa: a survey of managers in the public and private sectors" docx

báo cáo sinh học:" Managerial competencies of hospital managers in South Africa: a survey of managers in the public and private sectors" docx

... manage, perform four generic tasks. These include planning, organ- izing, leading and controlling. Planning involves defining goals and mapping out ways to reach them; organizing entails arranging ... audience of clinicians, educationists and health management experts, defined a list of health man- agement competencies and performance indicators to assist in the development of train...
Ngày tải lên : 18/06/2014, 17:20
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báo cáo sinh học:" Work satisfaction of professional nurses in South Africa: a comparative analysis of the public and private sectors Rubin Pillay" pot

báo cáo sinh học:" Work satisfaction of professional nurses in South Africa: a comparative analysis of the public and private sectors Rubin Pillay" pot

... has the advantage of promoting nurses within the ranks and reserving the more menial tasks to the less experienced and younger nurses, thereby offering a manageable workload and flexible working ... further developing themselves and growing within the ranks of their career. They also acknowledge experience and time dedicated to nursing, which provides much-needed recognition...
Ngày tải lên : 18/06/2014, 17:20
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Báo cáo sinh học: " Experimental infection of H5N1 HPAI in BALB/c mice" pdf

Báo cáo sinh học: " Experimental infection of H5N1 HPAI in BALB/c mice" pdf

... determine the potential sensitivity of studied H5N1 viruses to these anti- virals, amino acid sequences of the M2 and NA proteins were analyzed. Variants of influenza A viruses resistant to amantadine possessed ... con- tained Glu 92 in the NS1 and contained "avian-like" PDZ- domain ligand ESEV [19]. It was shown that the most recent H5N1 strains isolated in Southe...
Ngày tải lên : 18/06/2014, 18:20
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Báo cáo sinh học: " Mutational study of sapovirus expression in insect cells" docx

Báo cáo sinh học: " Mutational study of sapovirus expression in insect cells" docx

... have indicated that nucleotide point mutations increased the yields of SaV VLPs in insect cells, offering an alternative explanation for the increased expression levels of rVP1 and yield of VLPs. Results Wt, ... substitution in the VP1, whereas the open triangle in the VP2 gene did not change amino acid sequence. An RNA probe (anti-VP1) was used to monitor the...
Ngày tải lên : 18/06/2014, 22:20
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