Báo cáo sinh học: " Vaccinia virus A12L protein and its AG/A

Báo cáo sinh học: " Vaccinia virus A12L protein and its AG/A proteolysis play an important role in viral morphogenic transition potx

... the A12L protein during VV morphogenic transitions and regulation of A12L proteolysis. Conclusion By demonstrating that A12L protein and its cleavage at an N-terminal AG/A play an important role ... [7,8]. L4R, a DNA binding protein, plays an essential role in virus replication, being involved in an early stage of infection such as early tran- scri...

Ngày tải lên : 18/06/2014, 18:20

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Báo cáo sinh học: "Alpha-1 antitrypsin protein and gene therapies decrease autoimmunity and delay arthritis development in mouse model" potx

... as a serine proteinase inhibitor (serpin). It inhibits proteinase 3, neutrophil elas- tase, and cathepsin G. These serine proteases are released by joint invading neutrophils following inflammatory ... increase 3-4 folds, suggesting an important role in responding to inflammation in the human body. Increasing evidence indicates t hat hAAT is immunore- gulatory, anti-inflammatory...

Ngày tải lên : 18/06/2014, 19:20

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Báo cáo khoa học: Nuclear aggregates of polyamines are supramolecular structures that play a crucial role in genomic DNA protection and conformation potx

... genomic DNA preincubated with three differ- ent concentrations (1, 50 and 150 l M) of spermine (lanes c, c¢ and c¢¢), spermidine (lanes d, d¢ and d¢¢) or putrescine (lanes e, e¢ and e¢¢) and then exposed ... NAP (s-NAP; lanes c and c¢), medium-size NAP (m-NAP; lanes d and d¢) or large- size NAP (l-NAP; lanes e and e¢) and exposed to DNase I. Controls were the whole genomic D...

Ngày tải lên : 23/03/2014, 15:20

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Báo cáo sinh học: " Human neuronal cell protein responses to Nipah virus infection" docx

... ribonucleoprotein (hnRNP) F, guanine nucleotide binding protein (G protein) , voltage-dependent anion channel 2 (VDAC2) and cytochrome bc1 were present in abundance in the NiV-infected SK-N-MC cells in ... both cells and virus RNAs, and influence mRNA processing, trafficking, and stability [15,16]. The hnRNPs H and H2 found suppressed in NiV-infected cells bind to a gua...

Ngày tải lên : 18/06/2014, 18:20

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Báo cáo sinh học: " Dengue virus serotype infection specifies the activation of the unfolded protein respon" pot

... we analyzed the antiviral effect of Salubrinal on Dengue. Salubrinal was recently discovered as a small molecule inhibitor of the protein complex (containing the protein phosphatase 1 and its ... encoded XBP-1 protein (sXBP-1) is involved in the transcriptional activation of a number of genes including the ER man- nosidase-like protein EDEM which is involved in protein degra...

Ngày tải lên : 18/06/2014, 18:20

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Báo cáo sinh học: " Carlow Virus, a 2002 GII.4 variant Norovirus strain from Ireland" pot

... noroviruses in Japan between 1999 and 2004 [24]. Whether or not any of these amino acids have a role in altering binding specificity would require mutational analysis of the capsid protein, for ... Lordsdale virus [GenBank: CAA60256 ]. Transcription of the clones J3 (genomic), X1 (mutant) and 1A (sub genomic) resulted in bands of approximately 7.5 kb for both J3 and X1, and...

Ngày tải lên : 18/06/2014, 18:20

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Báo cáo sinh học: " Thottapalayam virus is genetically distant to the rodent-borne hantaviruses, consistent with its isolation from the Asian house shrew (Suncus murinus)" potx

... glycosylation of Hantaan virus glycoproteins and the role of oligosaccharide side chains in protein folding and intracellular trafficking. J Virol 2004, 78:5414-5422. 16. Lober C, Anheier B, Lindow S, ... 194–204 [10]. Studies of several hantaviruses have implicated the amino- and carboxy-termini in N protein interactions, and although the N protein amino-terminus of TPM...

Ngày tải lên : 18/06/2014, 18:20

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Báo cáo sinh học: " Seewis virus, a genetically distinct hantavirus in the Eurasian common shrew (Sorex araneus)" doc

... purposes) in Hungary and Finland (S. Arai and R. Yanagihara, unpublished observations). Found in woodlands, grasslands and hedgelands through- out Northern Europe, including Scandinavia and Great Britain ... NC_005223, NC_005225); and Sigmodontinae and Neotominae rodent-borne hantaviruses, including Andes virus (ANDV Chile 9717869, NC_003466, NC_003467, NC_003468) and Sin...

Ngày tải lên : 18/06/2014, 18:20

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Báo cáo sinh học: " Persistent expression of chemokine and chemokine receptor RNAs at primary and latent sites of herpes simplex virus 1 infection" pptx

... encoding the CCR1 and CCR5 chemokine ligands MIP-1α, MIP-1β and RANTES, and the CCR2 ligand MCP-1 were also strongly induced and persisted in cornea and TG during the latent phase. These and other ... Chemokines MIP-1α, MIP-1β, RANTES, and MCP-1, but not eotaxin-1, were also highly expressed and strongly induced in infected cornea at 3 and 10 dpi. IFN-γ and TNF-α were...

Ngày tải lên : 18/06/2014, 22:20

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Báo cáo sinh học: " EBV latent membrane protein 1 abundance correlates with patient age but not with metastatic behavior in north African nasopharyngeal carcinomas" pptx

... circulating antibodies directed to these viral proteins [20]. With this in mind we attempted to find an inverse relationship between the levels of anti-VCA and -EA IgG and IgA on one hand and the level ... pres- ence of aberrant levels of circulating antibodies directed against viral proteins, in particular against EBNA1 and lytic cycle antigens, such as EA (early antigen)...

Ngày tải lên : 19/06/2014, 08:20

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