Báo cáo hóa học: " Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences" potx
... article as: Amit and Hochberg: Development of targeted
therapy for bladder cancer mediated by a double promoter plasmid
expressing diphtheria toxin under the control of H19 and IGF2-P4
regulatory ... RESEARC H Open Access
Development of targeted therapy for bladder
cancer mediated by a double promoter plasmid
express...
... that
the DTA -H19 construct has a high therapeutic potential
and is a very promising candidate for ovarian cancer ther-
apy in humans.
Materials and methods
Cell culture
The human ovarian carcinoma ... effective anti-
tumor agents. Various gene therapy strategies for the treat-
ment of ovarian cancer are currently under development
and aim towards maximal trea...
... other
comorbidities, and the utilization of health care and
non-health care resour ces, laboral status and a stimated
cost of the fibromyalgia impact during the year before.
An eva luation was also made of patient ... intrinsica lly evaluates the emotional aspects:
anxiety and depression, and their impact upon social
aspects. It also evaluates patient functional capa...
... Joint Surg [Am]
2001, 83:1856.
9. Bellamy N, Buchanan WW: A preliminary evaluation of the
dimensionality and clinical importance of pain and disability
in osteoarthritis of the hip and knee. Clin ... sample size
needed for purposes of evaluation. The denominator was
the standard deviation of the score changes for those
patients in the test-retest analysis.
He...
... drawing
on alternate sources of information regarding a patient's
HRQL may be a useful source of information provided
that additional information is available to support the
validity of the ... inter-
ests.
Authors' contributions
HAH was the primary author on the manuscript and was
responsible for methodological and statistical support
throughout the study...
... 0.045), probably due to the
Figure 5 Means and standard deviations of the percentage of variance explained by the first 3 PCs (A) , and segmental loadings of the
dominant forearm, upper arm, trunk, ... KIU carried out data collection
and analysis, and drafted the manuscript. WAL developed the game. NDC
conducted subjective assessment and analysis of the...
... University of Delaware, Newark, DE, USA and
2
Department of Mechanical and Aeronautical
Engineering, Civil and Environmental Engineering, and Land, Air, and Water Resources, University of California, ... activation by electrical stimulation and the
force production by the muscle, such as release and
uptake of calcium by the sarcoplasmic reticulum, binding...
... generator
efficiency:
These equations illustrate that the transmission gear ratio
and transmission efficiency, the generator back-EMF con-
stant and the generator terminal resistance, and the elec-
trical load ... of the physiology of
walking and a novel design to best take advantage of the
underlying physiological principles. As muscle is ulti-
mately the origin...
... to
help.
The need for a dialog is based on the inherent uncertainty
about the state of the occupant and about what triggered
the alarm. Therefore, the goal of the dialog between the
occupant and the ... with the system design and testing, data analysis,
and drafting the article. All authors have read and
approved the final manuscript.
Acknowledgements...
... (ICC), and the x-axis lists different
normalization methods. The x-axis indicates the normalization
method used. The shorthand notation for the normalization method
is the name of the main approach ... Bethesda,
Maryland, USA.
3
Division of Cancer Epidemiology and Genetics, National
Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
Authors...