Báo cáo hóa học: " Treatment combining RU486 and Ad5IL-12 vector attenuates the growth of experimentally formed prostate tumors and induces changes in the sentinel lymph nodes of mice" doc

Báo cáo hóa học: " Treatment combining RU486 and Ad5IL-12 vector attenuates the growth of experimentally formed prostate tumors and induces changes in the sentinel lymph nodes of mice" doc

Báo cáo hóa học: " Treatment combining RU486 and Ad5IL-12 vector attenuates the growth of experimentally formed prostate tumors and induces changes in the sentinel lymph nodes of mice" doc

... Access Treatment combining RU486 and Ad5IL-12 vector attenuates the growth of experimentally formed prostate tumors and induces changes in the sentinel lymph nodes of mice Claudia Raja Gabaglia 1 , Alexandra ... combining RU486 and Ad5IL-12 vector attenuates the growth of experimentally formed prostate tumors and induc...
Ngày tải lên : 18/06/2014, 16:20
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Báo cáo hóa học: "Programmed cell death-1 (PD-1) at the heart of heterologous prime-boost vaccines and regulation of CD8+ T cell immunity" doc

Báo cáo hóa học: "Programmed cell death-1 (PD-1) at the heart of heterologous prime-boost vaccines and regulation of CD8+ T cell immunity" doc

... vaccination against HIV has expanded and resulted in hundreds of preclini- cal and clinical studies. Interestingly, the most promis- ing clinical regimens to date include: i) the RV144 landmark ... alternating the administration of a DNA vaccine with other vectors such as peptides, recombinant proteins, or viruses for the purpose of ind ucing and periodically replenishin...
Ngày tải lên : 18/06/2014, 16:20
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Báo cáo hóa học: "IL-2 as a therapeutic target for the restoration of Foxp3+ regulatory T cell function in organ-specific autoimmunity: implications in pathophysiology and translation to human disease" doc

Báo cáo hóa học: "IL-2 as a therapeutic target for the restoration of Foxp3+ regulatory T cell function in organ-specific autoimmunity: implications in pathophysiology and translation to human disease" doc

... signaling was required for the maintenance of the expression of the genes involved in the regulation of cell growth and metabolism [22]. Hence, IL-2 has a critical role in the homeostasis and competitive ... IL-2 levels in contexts of homeostasis and inflammation. Therefore, the waning of Treg cells, and ensuing breakdown in the self tolerance, could...
Ngày tải lên : 18/06/2014, 16:20
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báo cáo hóa học: " Treatment with gelsolin reduces brain inflammation and apoptotic signaling in mice following thermal injury" potx

báo cáo hóa học: " Treatment with gelsolin reduces brain inflammation and apoptotic signaling in mice following thermal injury" potx

... impairment with increased inflammation and apoptosis in the brain. Gelsolin, an actin-binding protein with capping and severing activities, plays a crucial role in the septic response. We investigated ... and participated in the writing of the manuscript. QC participated in the design of the study and the preparation of the animal model. JRK prepared all...
Ngày tải lên : 19/06/2014, 22:20
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báo cáo hóa học: "Fibrillar beta-amyloid peptide Aβ1–40 activates microglial proliferation via stimulating TNF-α release and H2O2 derived from NADPH oxidase: a cell culture study" doc

báo cáo hóa học: "Fibrillar beta-amyloid peptide Aβ1–40 activates microglial proliferation via stimulating TNF-α release and H2O2 derived from NADPH oxidase: a cell culture study" doc

... 48 hours. The amounts of inflamma- tory cytokines in the medium were detected by ELISA. The data presented in Fig. 4 and 5 are obtained by using kits for rat TNF-α and IL-1β (Quantikine, R&D ... each following addition), and the plates were blocked with 300 µl per well of blocking solution (PBS containing 1% BSA and 5% sucrose) for 2 hours at room temperature. Then...
Ngày tải lên : 19/06/2014, 22:20
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Báo cáo hóa học: " Strategy Escalation: An emerging paradigm for safe clinical development of T cell gene therapies Richard Paul Junghan" pdf

Báo cáo hóa học: " Strategy Escalation: An emerging paradigm for safe clinical development of T cell gene therapies Richard Paul Junghan" pdf

... dose chemotherapy and/ or whole body irradiation prior to T cell infusion in their TIL stud- ies in melanoma. With the burst of IL7 and IL15 that accompanies the lymphopenic state [12], the infused ... JC, Seipp CA, White DE, Steinberg SM: Use of tumor-infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma. A preliminary...
Ngày tải lên : 18/06/2014, 16:20
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báo cáo hóa học: " How do medical students value health on the EQ-5D? Evaluation of hypothetical health states compared to the general population" ppt

báo cáo hóa học: " How do medical students value health on the EQ-5D? Evaluation of hypothetical health states compared to the general population" ppt

... reported by 25.9% of the sample, 75.3% experienced illness in their close family. As the stu- dents have only been in their second year of medical train- ing including no practical training, no more ... a form of "bisectioning," where they begin by marking the best and worst states on the rating scale followed by the intermediate states. Since there is no EQ-5D...
Ngày tải lên : 18/06/2014, 19:20
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báo cáo hóa học: " Different gait tasks distinguish immediate vs. long-term effects of concussion on balance control" ppt

báo cáo hóa học: " Different gait tasks distinguish immediate vs. long-term effects of concussion on balance control" ppt

... spelling a common five-letter word in reverse, continuous subtraction by a certain number, and reciting the months of the year in reverse order [2,10,11,16,17]. At the beginning of each trial the ... given the specific task for that trial (e.g. count backwards by sevens starting at ninety-three). The subject then started walking and answering at the same time and s...
Ngày tải lên : 19/06/2014, 08:20
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Tài liệu Báo cáo khoa học: Erythrochelin – a hydroxamate-type siderophore predicted from the genome of Saccharopolyspora erythraea docx

Tài liệu Báo cáo khoa học: Erythrochelin – a hydroxamate-type siderophore predicted from the genome of Saccharopolyspora erythraea docx

... the C-terminal C 5 -domain, catalyzing the intramolecular nucleophilic attack of the L-hOrn 3 a-amino group onto l-haOrn 4 . Taking into account that the synthetases involved in the bio- synthesis ... enterobactin and coelichelin [6,7]. The C-terminal adenylation domain A 4 again is predicted to activate l-arginine, displaying 60% identity to the characterized A-domain of...
Ngày tải lên : 16/02/2014, 09:20
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Tài liệu Báo cáo khoa học: Control analysis as a tool to understand the formation of the las operon in Lactococcus lactis doc

Tài liệu Báo cáo khoa học: Control analysis as a tool to understand the formation of the las operon in Lactococcus lactis doc

... for example, in order to save energy and protein synthesizing capa- city. This would be preferable to placing all the genes involved in the pathway in the same operon; the cell can then respond ... quickly to changes in the environ- ment by changing the expression of only a few genes and using the protein-synthesizing capacity to express these genes when needed....
Ngày tải lên : 19/02/2014, 17:20
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