... factor (TNF-α) and interleukin (IL )-1 ; and ELISA kits for TNF-α, IL-1, IL-6, and IFN-γ were from R & D Systems. Trizol and transfec-tion reagents (Lipofectamine-2000, Lipofectamine-Plus, and Oligofectamine) ... mRNA for iNOS, TNF-α, IL-1β and IL-6 (Fig. 1b,d,f and 1h). AICAR attenuated the LPS/Aβ-induced production ofTNF-α, IL-1β, IL-6 and NO, and of their mRNA expres-sion, in a dose-dependent manner ... ERK pathway and atypicalprotein kinase C isoforms in exercise- and aminoimidazole-4-carboxamide-1-beta-D-riboside (AICAR)-stimulated glu-cose transport. J Biol Chem 2002, 277:2355 4-2 3562.48....