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báo cáo hóa học:" A practical approach for the validation of sterility, endotoxin and potency testing of bone marrow mononucleated cells used in cardiac regeneration in compliance with good manufacturing practice" docx

báo cáo hóa học:

báo cáo hóa học:" A practical approach for the validation of sterility, endotoxin and potency testing of bone marrow mononucleated cells used in cardiac regeneration in compliance with good manufacturing practice" docx

... testing in compliance with eu Pharmacopoeia2.6.1 (sterility) and the validation of the potency assay in an ATMP that is constituted of bone- marrow mononucle-ated cells used in cardiac regeneration. Materials ... types of potency assays can be envisioned: in vitro assays using cell systems and in vivo assays using animal models. As concerning the use of bone marrow mononucleated cells in cardiac repair, the ... potential of bone marrow cells has been testedinto hind limb ischemia animal models [12] and severalclinical studies are ongoing to evaluate the efficiency of the intra-arterial administration of...
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Báo cáo khoa học:

Báo cáo khoa học: "A Clustering Approach for the Nearly Unsupervised Recognition of Nonliteral Language" pdf

... than the baseline.Finally, we used our optimal configuration of TroFi, together with active learning and iterativeaugmentation, to build the TroFi Example Base, a publicly available, expandable ... deal of syntactic information in a single tag(each tag is an elementary tree from the XTAGEnglish Tree Adjoining Grammar). In additionto a word’s part of speech, they also encode in- formation ... UniversityBurnaby, BC, V 5A 1S6, Canadajbirke@alumni.sfu.ca, anoop@cs.sfu.caAbstract In this paper we present TroFi (TropeFinder), a system for automatically classi-fying literal and nonliteral usages of...
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Báo cáo y học:

Báo cáo y học: " A Practical Approach to Managing Patients with HCV Infection"

... Available Antiviral Therapy The current standard of therapy includes the combination of weekly pegylated interferon and daily ribavirin. The treatment duration and dosage, as well as the response ... panel. Although the serum aminotransferase level correlates poorly with liver histology, the ratio of aspartate aminotransferase (AST) to alanine aminotransferase (ALT) >1 is a dependable ... treatment candidacy is an important initial step in the management of chronic HCV infection as not all individuals may need or qualify for the treatment. Understanding the natural history, the different...
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Báo cáo y học:

Báo cáo y học: "A Practical Approach to Management of Chronic Hepatitis B"

... ALT Levels For many years, ALT has been used as a standard surrogate for the activity of CHB. Thus, ALT level in combination with HBV DNA level and histological activity has been used as a ... important parameters in determining indication, regimen, and duration of HBV treatment. Although interferon alfa-2b, lamivudine, and adefovir are all approved as initial HBV treatment, understanding ... Divisions of Gastroenterology and Transplantation, University of California, Irvine, California, USA. His current researches include natural history and management of hepatitis B and C and chemoprevention...
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Báo cáo khoa học: A new approach for distinguishing cathepsin E and D activity in antigen-processing organelles pdf

Báo cáo khoa học: A new approach for distinguishing cathepsin E and D activity in antigen-processing organelles pdf

... block any remainingactive sites, the material was further incubated with 5%BSA for an additional 2 h. After a wash with NaCl ⁄ Pi, the immobilized antibody was stored in NaCl ⁄ Picontaining0.02% ... activityCaD activityTAPACatE activityCaD activityTAPACatE activityCaD activity A BCFig. 5. Distribution of TAPA, CatE and CatD activity in subcellularfractions of the cell lines (A) HaCaT, (B) ... organelles.Therefore it could be used to study the involvement of these proteinases in protein degradation and the processing of invariant chain. An assay combi-ning a new monospecific CatE antibody...
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báo cáo hóa học:

báo cáo hóa học:" A systematic approach to biomarker discovery; Preamble to "the iSBTc-FDA taskforce on immunotherapy biomarkers"" docx

... Abstract The International Society for the Biological Therapy of Cancer (iSBTc) has initiated in collaboration with the United States Food and Drug Administration (FDA) a programmatic look at ... Palucka to evaluate current approaches to the validation of known immune response biomarkers and the standardization of the respective assays to enhance the likelihood of obtaining informative ... vary widely and are likely to make the task of consolidating clinical trials results even moredaunting.vii. Standardization, Centralization, Validation Although the principles of standardization...
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Báo cáo hóa học:

Báo cáo hóa học: " A novel method for neck coordination exercise – a pilot study on persons with chronic non-specific neck pain" docx

... of the study, carried out the data acquisition, and the statistical analyses and drafted the manuscript. MBJ participated in the design and coor-dination of the study, the statistical analyses ... self-reported characteristicsSelf-rated pain was assessed as pain at the moment and measured within a week before the day of testing on a blank 100 mm visual analogue scale (VAS), on which 0 ... tests The correlation analyses of the sensorimotor variablesrevealed that repositioning VE and ROM from the cervicalrotation test and Ra and Tr area from the postural sway testPerformance of the...
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báo cáo hóa học:

báo cáo hóa học: "A binary method for simple and accurate two-dimensional cursor control from EEG with minimal subject training" potx

... per-formed the data analysis, and drafted and revised the manuscript. OB developed the Matlab-based software sys-tem for EEG data acquisition and processing within whichTK's paradigm-specific ... data analysis, and assisted with critically revising the manuscript. CSH provided invaluable guidance and criti-cal input for revising the manuscript. PL assisted with datacollection and analysis, ... revising the manuscript. All authors read and approved the final manuscript.Additional materialAcknowledgementsThis research was supported by the Intramural Research Program of the NIH (National...
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Tài liệu Báo cáo khoa học:

Tài liệu Báo cáo khoa học: "A Practical Solution to the Problem of Automatic Word Sense Induction" doc

... even for practical purposes, we can not claim that our algorithm is capable of finding all the fine grained distinctions that are listed in manually created dictionaries such as the Longman ... associations to palm are all in the upper half of the scale and not very distinct. The two expected clusters for palm, one relating to its hand and the other to its tree sense, have essentially been ... is exactly what we want in sense induction. In an attempt to provide a quantitative evaluation of our results, for each of the 12 ambiguous words shown in table 1 we manually assigned the top...
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Báo cáo khoa học: A kinetic approach to the dependence of dissimilatory metal reduction by Shewanella oneidensis MR-1 on the outer membrane cytochromes c OmcA and OmcB potx

Báo cáo khoa học: A kinetic approach to the dependence of dissimilatory metal reduction by Shewanella oneidensis MR-1 on the outer membrane cytochromes c OmcA and OmcB potx

... GTGTGATCTGCAACTGTTOMCA-PBAD-F CACCGAGGAATAATAAATGATGAAACGGTTCAATTTCOMCA-PBAD-R TTAGTTACCGTGTGCTTCOMCB-PBAD-F CACCGAGGAATAATAAATGATGAACGCACAAAAATCAOMCB-PBAD-R TTACATTTTCACTTTAGTShewanella oneidensis ... CACACTGCAACCTCTGGTOMCA-KO-R ACTGTCAATAGTGAAGGTOMCB-KO-F CCCCATGTCGCCTTTAGTOMCB-KO-R TCGCTAGAACACATTGACOMCA-F ATGATGAAACGGTTCAATOMCA-R TTAGTTACCGTGTGCTTCOMCB-F CTGCTGCTCGCAGCAAGTOMCB-R GTGTGATCTGCAACTGTTOMCA-PBAD-F ... MR-1R was used as a positive control to display omcA(lane 1) and omcB (lane 6). DNA standards are indicated at the left and right of the agarose gels. (B) Visualization and separation of high...
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