báo cáo hóa học:" Intrinsic and extrinsic factors influencing the clinical course of B-cell chronic lymphocytic leukemia: prognostic markers with pathogenetic relevance" docx
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Journal of Translational Medicine
Open Access
Review
Intrinsic and extrinsic factors influencing the clinical course of B-cell
chronic lymphocytic ... of CLL cells, hence eventu-
ally influencing the clinical aggressiveness of the disease,
are divided into " ;intrinsic factors& quot;, ma...
... study, and the range of age differences may explain
the different results. On the other hand, the epidemiolog-
ical figures of oral diseases can significantly influence the
pattern of the causes of ... conceived the study, performed the statistical analy-
sis and interpretation of data, and drafted the manuscript.
MAP participated in the collection, analysi...
... completes the proof of Theorem 2.
4. Smoothness of the intersection local time
In this section, we consider the smoothness of the intersection local
time. Our main object is to explain and prove the ... Existence of the intersection local time
The aim of this section is to prove the existence of the intersection
local time of S
H
and
S
H
, for an H =
1...
... Liebner S., Andbjer B., Kalbacher H., Wolburg H.,
Haller H., and Fuxe K. Organization of choroid plexus epithe-
lial and endothelial cell tight junctions and regulation of
claudin-1, -2 and -5 expression ... analysis, these transfectants demonstrate the presence of claudin-1 protein in the
cytoplasm, with small amounts in the nucleus. When cells are transfected with...
... atoms of Ala59 and
Glu61 of one subunit and with the main chain nitro-
gen of Asn114¢ of the other subunit. The contacts of
the ribityl chain to His89 and Lys138¢ are mediated by
a net of water ... behaviour of the binding sites within
a pentamer which depends on the specific nature of the
inhibitor molecule, particularly depending on the
length of th...
... steps that govern the nucleotide
dependency of the enzyme and the inhibition observed with
ADP.
MATERIALS AND METHODS
Purification of the recombinant
Cl
-ACL
Construction of the expression vector ... decreased the affinity of
the enzyme for the second molecule by a factor of 23. ADP
was a competitive inhibitor of ATP with a K
i
value of
0.037 ± 0.006 m
M
. T...
... verify the influence
of the nature of the amino acid at this position on
determination of the cleavage sites and on the amount of
their hydrolysis. This series of peptides was chosen because
the ... of
hydrolysis and the variations of the cleavage sites were
evaluated under different conditions of temperature and
salt concentration. The relative amount o...
... accumulation in these cells,
through the uptake of oxLDL/LDL, is believed to be of
fundamental importance to the etiology and pathogenesis
of atherogenesis and atherosclerosis and other chronic
inflammatory ... treated with a
range of doses of GW3965 (Figure 2D) or LXR-623 (Figure
2E). Since the potency of these ligands for activation of rat
LXRα or LXRβ is not k...
... cells[20] or
Sequence and GO analysis of the miR-302 cluster and miR-520 clusterFigure 8
Sequence and GO analysis of the miR-302 cluster and miR-520 cluster. The members of the miR-302 and miR-520
clusters ... as the reference for the miRNA expression
array assay. The test sample was labelled with Hy5 and the
reference with Hy3. After labelling, the sa...
... exception of acetaldehyde and hexanaldehyde,
all other gases quantified in the headspace of the HL60
cells were either near the detection limit of the GC-MS sys-
tem, or were evolved solely from the ... illustrating the time-dependent increase of
acetaldehyde concentration in the headspace above the
HL60 cells. The asymmetry of the acetaldehyde peak is a
result...