... section and scheme of the coronal section at E14.5 in (F). (A) At E11.5, HSF2 is expressed in forebrain, midbrain and in hindbrain except for the midbrain, hindbrain midline. Surprisingly, the ... before and after birth in mouse brains[122,124]. No HSF4 DNA-binding activity wasreported in the developing mouse brain so far. How-ever, Hsf4b is expressed in the adult mouse brain,including ... ubiquitinated and oxydated proteins,as well as an increased sensitivity to oxidative stress, isalso observed [145]. In conclusion, HSF2 acts in brain and neuronal development by fine tuning, and...