... eclipsedconformation, but as presented in the figure they are all equal to 180°. A BFig. 7. Two examples of a Ramachandran diagram. (A) Plot for Erwinia chrysanthemi L-asparaginase, one of the largest ... in the absence of a substrate,product, or inhibitor, the catalytic domain of Lon mayadopt an inactive conformation. This is a lesson worthremembering. A practical approach to evaluatingprotein ... consequenceof the inactive conformation of the catalytic residueswas the inability of the two aspartate side chains to bind a catalytic divalent metal cation in a coordinatedfashion. Subsequent...