... 4 Drug- Metabolizing Enzymes,Transporters, and Drug Drug InteractionsSTEVEN W. LOUIE, and MAGANG SHOUDepartment of Pharmacokinetics and Drug Metabolism, Amgen, Inc.,Thousand Oaks, ... described in Chapter 7. In this chapter, the reader will obtain insight into the strategies used to design experiments for characterizing drug metabolism properties and addressing drug metabolism ... LOUIEDepartment of Pharmacokinetics and Drug Metabolism Amgen, Inc.Thousand Oaks, CaliforniaCHUANG LU Drug Metabolism and Pharmacokinetics Millennium Pharmaceuticals, IncCambridge, Massachusettsxviii...