structure and interpretation of computer programs
structure and interpretation of computer programs
... matter of this book involves us with three foci of phenomena: the human mind, collections of computer programs, and the computer. Every computer program is a model, hatched in the mind, of a ... Poorly-Understood and Sloppily-Formulated Ideas''``The Structure and Interpretation of Computer Programs& apos;' is the entry-level subject in computer science at the Massachusetts Institute of ... source of the exhilaration associated with computer programming is the continual unfolding within the mind and on the computer of mechanisms expressed as programs and the explosion of perception...
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Tài liệu Báo cáo khoa học: Structure and function of active chromatin and DNase I hypersensitive sites pdf
... withbinding of both MOF and Tip60 (equivalent to Esa1in yeast NuA4) [124,130]. However, in human cellsdepletion of MOF, but not Tip60, results in reducedglobal levels of AcH4-K16 and defective ... acetylation and deacetyla-tion, and transient recruitment of remodellers and transcription factors.A cycle of transcription commences with the recruit-ment of transcription factors and co-factors ... A (1979) Involvement of histone H1 in the organization of the nucleosome and of the salt-dependent superstructures of chromatin.J Cell Biol 83, 403–427.Active chromatin and DNase I hypersensitive...
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Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx
... culturedhippocampal neurons.Fig. S4. Domain structure of MAP2 and the alignment of v-KIND-binding core (BD) region of MAP2 CD2domain (702–744 aa) in human, mouse and GallusThis supplementary material ... stability and rear-rangement of microtubules in neuronal dendrites[13–15] and is associated with some neurological and psychiatric disorders [16,17]. However, the structure function relationship of ... α-FlagKIND2-FlagΔGEF-FlagABFig. 1. Domain structure of the MAP2-asso-ciated RasGEF v-KIND and its dendritic tar-geting via KIND2 domain. (A) Structures of the v-KIND. KIND1, KIND2, coiled-coil (CC),RasN and RasGEF domains....
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Tài liệu Body Size: The Structure and Function of Aquatic Ecosystems pptx
... multiple stressors and taxon-specificsolutions can conspire to reduce the likelihood of detecting clear patterns.We believe that our understanding of the structure and functioning of streamecosystems ... NC 28557 and Virginia Institute of Marine Science, The College of William and Mary, Gloucester Point, VA 23062.Michael C. Marshall Department of Zoology and Physiology, University of Wyoming, ... predatory fish and invertebrate prey. New Zealand Journal of Marine and Freshwater Science, 34, 557–567.Usio, N. & Townsend C. R. (2004). Roles of crayfish: consequences of predation and bioturbation...
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Tài liệu Báo cáo khoa học: Structure and function of plant aspartic proteinases pptx
... isoforms by the excision of the prosegment and of most of the PSI [21]. Conversely to what has been foundin vivo [31], heavy and light chains of the processed forms of recombinant cyprosin are ... by the prosegment, but also bythe 13 residues of the N-terminal of the mature enzyme and by the ÔflapÕ. The anchorage of the prosegment and of part of the N-terminus in the active site cleft is ... and C-terminal domain in red. (B) Ribbon representation of the structure of the PSI domain of barley prophytepsin [25] (N-terminal domain,blue; C-terminal domain, red). (C) Model structure of...
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Tài liệu Báo cáo khoa học: a-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes doc
... analysis of the DNA of different Conus specieshas already revealed a large number of a-conotoxinsequences [45] and the identification of further specificnAChR ligands is likely. The advantage of a ... population of a-BTX binding a7* nAChRs whichis mainly localized perisynaptically, and a less abundantpopulation of a3* nAChRs which contain a5andb4subunits and in some cases b2 subunits, and is ... use of a-conotoxins MII and AuIB further dissected and correlated the combinato-rial and functional heterogeneity of the slowly decayingpopulation [77]. In this study, two long events of 25...
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Tài liệu Báo cáo khoa học: Cold survival in freeze-intolerant insects The structure and function of b-helical antifreeze proteins pdf
... [31,32,36] and their three-dimensional structures were determined [34,37–40]. Insubsequent sections, we describe the structure and dynamics of each protein, and present a comparison of s bwAFP and TmAFPwitheachotherandwithproteinsthathaveasimilar ... and TmAFPwitheachotherandwithproteinsthathaveasimilar fold. Structure of sbwAFP and TmAFPThe structure of sbwAFP has been determined by X-raycrystallography to 2.5 A˚ and by NMR at both 30 °Cand5 °C ... to T hr49) and TmAFP (blue, residuesAsn29fiGly41). Letters de note the five residues of on e of the threesides of s bwAFP o r s ix residues of on e of two sides of T mAFP. T hestrands that make...
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Tài liệu Báo cáo khoa học: Complete subunit sequences, structure and evolution of the 6 · 6-mer hemocyanin from the common house centipede, Scutigera coleoptrata pptx
... hemocyanin of which the complete molecular structure is known. This allows us to compare structure, and intra- and intermolecular evolution of hemocyanins fromMyriapoda, Crustacea and Chelicerata.Materials ... submitted to MALDI-TOF analysis and assigned to distinct subunits.Fig. 1. SDS/PAGE and immunoblotting of S. coleoptrata hemocyanin.About 10 lg of total hemolymph protein (HL) and 3 lgofpurifiedhemocyanin ... composed of 12 HcA, 12 HcB, six HcC and six HcD polypeptides. Thus the basic building block of the hemocyanin, the hexamer, most likely contains twocopies of each HcA and HcB, and single copies of...
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Tài liệu Báo cáo Y học: A Raman optical activity study of rheomorphism in caseins, synucleins and tau New insight into the structure and behaviour of natively unfolded proteins pot
... longer-chain (and nonglobular) versions of the structure of the Bowman±Birk inhibitor in Fig. 6 . TheX-ray crystal structure 1 pi2 reveals that the /,w angles of most of the residues of the Bowman±Birk ... orm of b strand [18].The positive bands at » 1675 cm)1in the amide I r egion of the ROA spectra of b-andj-casein, which originate mainlyin the peptide C O stretch, are characteristic of ... theme of PPII structure and rheomor-phism is explored by a comparative ROA study, supple-mented with DSC, of caseins, synucleins and tau, togetherwith several mutants of a-synuclein and tau...
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