... enzymeclan consists of a group of enzyme families with acommon ancestry, very similar tertiary structure andconserved catalytic machinery and reaction mechanism[79]. Here we propose that a clan of ... Glucoamylasestructural, functional, and evolutionary relationships.Proteins 29, 334–347.65 Williamson MP, Le Gal-Coeffet MF, Sorimachi K,Furniss CS, Archer DB & Williamson G (1997) Func-tion of conserved ... CBM20-CBM21evolutionary tree. This provides a basis for the joining of the two CBMs into a common clan.Results and DiscussionLocation of SBD modules in CBM20 and CBM21With regard to the location of the...