... structure of < /b> TenA. (A) Amino acid sequence of < /b> HP-TenA. The beginning and end of < /b> secondary structureelements of < /b> HP-TenA are shown in the bottom line. (B) Stereo view of < /b> a cartoon representation of < /b> the ... enzymes of < /b> this family, despite its close proximity to the sub-strate, is unable to compensate for the absence of< /b> Tyr47 because its orientation is incorrect with respectto the substrate. Mutation ... 6233References1 Settembre E, Begley TP & Ealick SE (2003) Structuralbiology of < /b> enzymes of < /b> the thiamin biosynthesispathway. Curr Opin Struct Biol 13, 739–747.2 Morett E, Korbel JO, Rajan E, Saab-Rincon...