Báo cáo khoa học: Structural analysis of the jacalin-related lectin MornigaM from the black mulberry (Morus nigra) in complex with mannose ppt

Báo cáo khoa học: Structural analysis of the jacalin-related lectin MornigaM from the black mulberry (Morus nigra) in complex with mannose ppt

Báo cáo khoa học: Structural analysis of the jacalin-related lectin MornigaM from the black mulberry (Morus nigra) in complex with mannose ppt

... 2 that delineate the carbohydrate-binding cavity of the lectin protomer). A closer examination of the structure of the binding sites indicates that specificity of the Mora- ceae lectins is primarily ... Structural analysis of the jacalin-related lectin MornigaM from the black mulberry (Morus nigra) in complex with mannose Anja Rabijns 1 ,...
Ngày tải lên : 30/03/2014, 20:20
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Báo cáo khoa học: Structural analysis of the N-glycans of the major cysteine proteinase of Trypanosoma cruzi Identification of sulfated high-mannose type oligosaccharides doc

Báo cáo khoa học: Structural analysis of the N-glycans of the major cysteine proteinase of Trypanosoma cruzi Identification of sulfated high-mannose type oligosaccharides doc

... (oligosaccharides from C-terminal domain or from the whole protein) and using different equipment. Therefore, the retention of water can be explained taking into account its strong interac- tion with the negative ... structures of the N-linked oligosaccharides present in cruzipain. HPAEC analysis of the total neutral oligosaccharide fraction obtained from the C-t...
Ngày tải lên : 23/03/2014, 15:20
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Báo cáo khoa học: Functional analysis of a murine monoclonal antibody against the repetitive region of the fibronectin-binding adhesins fibronectin-binding protein A and fibronectin-binding protein B from Staphylococcus aureus pot

Báo cáo khoa học: Functional analysis of a murine monoclonal antibody against the repetitive region of the fibronectin-binding adhesins fibronectin-binding protein A and fibronectin-binding protein B from Staphylococcus aureus pot

... these, there is the possibility that, through the effect of the proximities of the antibody-binding and Fn-binding sites, the interaction of the repeat with Fn may be sterically hindered in the ... fibronectin. The C-terminal domain of fibronectin-binding protein A is organized into 11 tandem repeats, six of which bind the ligand with high affinity; other sites...
Ngày tải lên : 06/03/2014, 22:21
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Báo cáo khoa học: Structural analysis of lipopolysaccharides from Haemophilus influenzae serotype f Structural diversity observed in three strains ppt

Báo cáo khoa học: Structural analysis of lipopolysaccharides from Haemophilus influenzae serotype f Structural diversity observed in three strains ppt

... most of the steps in the biosynthesis of the oligosaccharide portion of the LPS molecules. The genes lpsA, lic2A and lgtC encode glycosyltransferase enzymes involved in the addition of the globoside ... representative ofthediversitywithinthetypefcluster. Previous studies of LPS from H. in uenzae have resulted in a structural model consisting of a conserved...
Ngày tải lên : 23/03/2014, 21:20
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Tài liệu Báo cáo khoa học: Crystal structure of thiamindiphosphate-dependent indolepyruvate decarboxylase from Enterobacter cloacae, an enzyme involved in the biosynthesis of the plant hormone indole-3-acetic acid doc

Tài liệu Báo cáo khoa học: Crystal structure of thiamindiphosphate-dependent indolepyruvate decarboxylase from Enterobacter cloacae, an enzyme involved in the biosynthesis of the plant hormone indole-3-acetic acid doc

... molecules of the cofactors ThDP and Mg 2+ . The ThDP binding sites are located in narrow clefts at the interfaces formed by the PYR domains from one subunit and the PP domains of the other subunit within ... orientation of the aminopyrimidine ring, are conserved in all ThDP-dependent enzymes. One of these, the hydrogen bond between the N1¢ atom of the pyrim...
Ngày tải lên : 20/02/2014, 11:20
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Báo cáo khoa học: Structural diversity of angiotensin-converting enzyme Insights from structure–activity comparisons of two Drosophila enzymes docx

Báo cáo khoa học: Structural diversity of angiotensin-converting enzyme Insights from structure–activity comparisons of two Drosophila enzymes docx

... in ANCE and ACER, respectively, which in our models are pointing away from the inhibitor so that the change in the size of the side chain may have minimal effect on binding. Val956 of C-domain ... studies con- firm many of the predictions regarding the identity of the active-site residues and, in the case of tACE, iden- tify other side chains involved in...
Ngày tải lên : 23/03/2014, 11:20
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Báo cáo khoa học: Solution structure of long neurotoxin NTX-1 from the venom of Naja naja oxiana by 2D-NMR spectroscopy pot

Báo cáo khoa học: Solution structure of long neurotoxin NTX-1 from the venom of Naja naja oxiana by 2D-NMR spectroscopy pot

... Considering flexibility of l oop II in receptor binding, substitution of Gly33 with Ser (a common residue in other long neurotox- ins) may lower mobility, thereby affecting the binding affinity of NTX-1. Acknowledgements The ... side chains (such as Arg and Lys, similar to the corresponding residues in a-CTX that are involved in receptor binding) would be i n teresting bec...
Ngày tải lên : 23/03/2014, 13:20
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Tài liệu Báo cáo khoa học: Mutational analysis of plasminogen activator inhibitor-1 Interactions of a-helix F and its neighbouring structural elements regulates the activity and the rate of latency transition pdf

Tài liệu Báo cáo khoa học: Mutational analysis of plasminogen activator inhibitor-1 Interactions of a-helix F and its neighbouring structural elements regulates the activity and the rate of latency transition pdf

... behaviour of the serpin. Complex formation between serpins and their cognate proteases is fuelled by the thermodynamic properties of the serpin. Accordingly, insertion of the RCL as s4A and the ensuing ... linkage of the active site Ser of the protease to the carboxyl group of P 1 by an ester bond and insertion of the N-terminal part of the RCL as strand...
Ngày tải lên : 20/02/2014, 11:20
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Báo cáo khoa học: Structural analysis ofN-glycans of the planarian Dugesia japonica. ppt

Báo cáo khoa học: Structural analysis ofN-glycans of the planarian Dugesia japonica. ppt

... Five minutes after the sample had been injected, the concentration of ammonium acetate, pH 9.0, was increased linearly to 0.2 m in the first 20 min, Fig. 6. Sugar component analysis of pN4. The ... were tagged with the fluorophore 2-aminopyridine. Lyophilized samples were heated at 90 °C for 60 min with 20 lL of pyr- idylamination reagent, and then heated at 80 °C for 35...
Ngày tải lên : 28/03/2014, 23:20
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Tài liệu Báo cáo khoa học: Structural effects of a dimer interface mutation on catalytic activity of triosephosphate isomerase The role of conserved residues and complementary mutations pptx

Tài liệu Báo cáo khoa học: Structural effects of a dimer interface mutation on catalytic activity of triosephosphate isomerase The role of conserved residues and complementary mutations pptx

... bond with the backbone CO of F102. Fur- thermore, the orientation of the side chain of the two residues brings the guanidinium plane and the aro- matic ring of F102 into close proximity, with ... only critical for the stability of the dimer, it may also be involved in maintaining the integrity of the active site. These results clearly suggest that the d...
Ngày tải lên : 18/02/2014, 11:20
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