... Turkey 3. Istanbul University, Faculty of Medicine, Department of Biochemistry, Istanbul, Turkey 4. Istanbul University, Faculty of Medicine, Department of Histology and Embryology, Istanbul, ... suggest the necessity of multidisciplinary study designs which take into ac-count different characteristics of the tissues involved in host tissue – bone graft interactions. The use of adjunctive ... could be partially explained by the basic tissue effects of HBOT and local characteristics of the bone grafts. Collagen synthesis from fibroblasts and the formation of osteoid substance by osteoblasts...