... MINIREVIEW Collective behavior in gene regulation: Metabolic clocks and cross-talking Michele M. BianchiDepartment of Cell and Developmental Biology, University ... for a single cell over time and theaverage over the statistical ensemble of individuals at agiven time coincide. In the ergodic hypothesis, genes are generallydivided into housekeeping genes, ... (nondomestic) growth. Interestingly,yeast growing in a colony undergoes cyclic changes in metabolism, from acidic to alkaline [46]. Furthermore,alkali-producing colonies can entrain colonies in theacidic...