... Takentogether, these observations suggest that sterol synthe-sis may play a crucial role in cell polarization and in the function of PAKs and sterol biosynthetic proteinsin the same pathway(s). Therefore, ... the activity of this SE-synthesiz-ing enzyme. Considering the importance of sterols forcell polarization, and the interactions between PAKs and proteins catalyzing sterol synthesis and storage, ... Nevertheless, the phenotypes of mutants defective in ergosterolsynthesis clearly demonstrate the importance of sterolsfor polarization during mating [25,28,29]. On the other hand, the observation...