Báo cáo khoa học: Crystal structures of open and closed forms of cyclo⁄maltodextrin-binding protein pptx
Báo cáo khoa học: Crystal structures of open and closed forms of D-serine deaminase from Salmonella typhimurium – implications on substrate specificity and catalysis pptx
... resemblethe open and closed forms, respectively, of other Fold-type II PLP-dependent enzymes. The solvent accessiblesurface areas of StDSD in the open and closed forms are 16 994 and 16 540 ... Bharath et al. Crystal structure of D-serine deaminaseFEBS Journal 278 (2011) 2879–2891 ª 2011 The Authors Journal compilation ª 2011 FEBS 2891 Crystal structures of open and closed forms of D-serinedeaminase ... under crystallization conditions orfrom the crystals. Thus, the WtDSD and SeMetDSD structures can be viewed as open and closed forms of the enzyme.In the WtDSD structure, two segments (68–71 and 234–239)...
- 13
- 359
- 0
Báo cáo khoa học: Crystal structures of open and closed forms of cyclo⁄maltodextrin-binding protein pptx
... open form.Results and DiscussionOverall structures of TvuCMBP–ligand complexesThe crystal structures of TvuCMBP liganded witha-CD, b-CD and G4 have been determined at 1.7, 1.8 and 1.55 A˚resolutions, ... Asp83 and Glu129 form hydrogen bonds with different atoms,O2 of Glc-2(CD), O3 of Glc-3(CD), and O3 of ABFig. 4. Stereo views of N-domains involvedin ligand binding in the open forms of TvuCMBP ... forEcoMBP, and the bending and twist angles (35° and ABCDEFig. 6. Structures of the hinge regions of TvuCMBP–a-CD and TvuCMBP–G4. (A, B) Comparison of the residues in and aroundhinge-1 and hinge-2....
- 12
- 355
- 0
Tài liệu Báo cáo khoa học: Crystal structures of the regulatory subunit of Thr-sensitive aspartate kinase fromThermus thermophilus pdf
... thermostability of TtAK. Comparison of the crystal structures of TtAKb and CgAKb was expected to elucidate the mechanism of the elevated thermostability of TtAKb.In this article, we describe the crystal structures ... denaturation temperature (Tm )of4 0°C. Comparison of the crystal structures of TtAKb and the regulatory subunit of C. glutamicumAK showed that the well-packed hydrophobic core and high Pro contentin ... bondsin the crystal structures. To estimate the changes in Gibbsfree energy (DG) of TtAKb and CgAKb, we calculated thesolvent-accessible surface area of two native and denatured protein forms using...
- 13
- 785
- 0
Tài liệu Báo cáo khoa học: Crystal structures of a bacterial 6-phosphogluconate dehydrogenase reveal aspects of specificity, mechanism and mode of inhibition by analogues of high-energy reaction intermediates pdf
... These structures provideinsight into the key features of PDH specificity and mode of inhibition of the enzyme.Results and DiscussionStructural analysis and model quality Crystal structures of ... Catalytic reaction of PDH and two intermediate states. (B) Structures and numbering of the inhibitors PEX (two resonance forms) and PEA.6-Phosphogluconate dehydrogenase ligand complexes R. Sundaramoorthy ... and 148–153. A similar difference is observedwhen comparing the cofactor domains of the OaPDH and TbPDH structures [13]. The superposition of sub-unit A of complex I onto subunits A, B, C of...
- 12
- 452
- 0
Báo cáo khoa học: Crystal structures of the apo form of b-fructofuranosidase from Bifidobacterium longum and its complex with fructose pot
... the b-propeller and b-sandwichdomains involve contacts of IV and V blades and b-strands (1–6) from the internal b-sheet of the b-sand-wich domain. The last four amino acids of the nativesequence ... thenative and recombinant protein were 58 091 and 59 156 Da, respectively. The results of MS of recombi-nant b-fructofuranosidase are close to the theoreticalvalue of the molecular mass. A peak of ... concentrations of ammonium chloride. Theenzyme was very sensitive to acidity changes in crystal- lization conditions and formed different crystal forms depending on the pH value.Several crystal forms of...
- 17
- 521
- 0
Báo cáo khoa học: Crystal structures of Nipah and Hendra virus fusion core proteins ppt
... constructs of both NiV and HeV F proteins. Aschematic diagram of NiV and HeV F proteins with the location of structurally significant domains is given. The listed sequences of HR1 (137–178) and HR2 ... effects of HR2 onviral fusion and formation of the fusion core structure.The results also show that the HR2 proteins of NiV and HeV are functionally and structurally interchange-able, and this ... Metapneumovirus and the new Avulavirus and Henipavirus) [6,10,11]. Likeother paramyxoviruses, NiV and HeV consist of twosurface glycoproteins on the viral surface, termed thefusion (F) protein and glycoprotein...
- 10
- 478
- 1
Báo cáo khoa học: Crystal structures of the human SUMO-2 protein at 1.6 A and 1.2 A resolution ppt
... NMRstructure of SUMO-1 and the crystal structure of yeastACDBFig. 2. Photographs and electron density maps of the SUMO-2 crystals. Shown in (A) and (B) are two different crystal forms I and II obtaine ... type II crystal, r efinements and map calculations also usedSHELX-97 [14]. Substitution of side chains, addition of water molecules, manualadjustment of the protein models and rebuilding of theN- ... Surface properties of SUMO proteins.The molecular surface of SUMO-2 (type I crystal) isshownin(A )and( C);thatoftheSUMO-1modelisshownin(B )and( D).Thecharge potentials in ( A) (C) and (D) a re cal-culated...
- 9
- 441
- 0
Báo cáo khoa học: Crystal structures of HIV protease V82A and L90M mutants reveal changes in the indinavir-binding site potx
... con-tained a 1 : 1 ratio, by volume, of reservoir solution and protein. The final drop was typically 2 lL, and crystals grewin 2–7 days. The wild-type and PRV82Acrystals wereobtained using 0.05Mcitrate/phosphate ... at the termini and the variable surface loops of residues 16–18, 37–41, and 67–69 of both subunits in all structures, except for the largervalues at 50–52 and 51¢)54¢ in PR, and 80–81 in PRL90M(Fig. ... However, mutations of Arg8 and Glu21 are rarely observed in resistant isolates [2].One of the conformations of the side chain of Lys45 in PR forms hydrogen bonds with the Od2 of Asp30, whichis...
- 9
- 355
- 0
Báo cáo khoa học: Crystal structures of bovine odorant-binding protein in complex with odorant molecules doc
... UNDPhe89A Alt Open Open Alt Alt Open B Alt Alt Alt Closed Alt Closed Volumes of the cavitiesA 396 491 504 396 400 443B 377 378 401 375 377 377Ó FEBS 2004 Crystal structures of bOBP–odorant ... 1).ResultsBinding of AMA and odorants in solutionThe dissociation c onstants of the AMA–OBP c omplexes fo rthe bovine and porcine OBP isoforms were, respectively, 1 .0 and 1.5 lM and the corresponding ... AMA and theconcentration of AMA.Crystallization, data collection and refinement of bovine OBPExcept for the bOBP–UND complex, bOBP crystals wereobtained by m icrodialysis of a 1 0 mgÆmL)1protein...
- 11
- 251
- 0
Báo cáo khoa học: Crystal structures of Aedes aegypti kynurenine aminotransferase potx
... the PLP and PMP forms, 87% of the residues were in the most favored regions of the Ramachandran plot. Although Tyr286 (A) and (B)in both forms fall within a disallowed region of theRamachandran ... Asp112 and Lys6 (3.96, 4.15 A˚) and Asp112 and Arg7 (3.48, 3.55 A˚) of the opposite subunits. InAeKAT structures, Cys284 (A) and Cys284 (B) withdistances of 3.46 A˚(PLP form) and 3.57 ... containing10 mgÆmL)1 of protein, 30% (w ⁄ v) PEG 1000, and 0.1 m of Tris ⁄ HCl at pH 8.5. Refinement of preliminary crystalliza-tion conditions resulted in the growth of quality crystals ina solution...
- 9
- 329
- 0
Từ khóa: báo cáo khoa học mẫubáo cáo khoa học y họcbáo cáo khoa học sinh họcbáo cáo khoa học nông nghiệpbáo cáo khoa học lâm nghiệpbáo cáo khoa học thủy sảnNghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngBáo cáo quy trình mua hàng CT CP Công Nghệ NPVMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Kiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtchuong 1 tong quan quan tri rui roGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtBÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIĐổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ