... followed were in accordance with institutional guidelines involving human subjects. Vaccine description All adults were vaccinated with Influenza Virus Vaccine Fluzone® (inactivated Influenza ... BioRad, Hercules, CA). Cytokine determination Serum cytokines [Interleukin-2 (IL-2), Interferon gamma (IFN-γ), Interleukin-4 (IL-4), Interluekin-10 (IL-10)] were determined by sandwich ELISA (Bio-source, ... by vaccination may contribute to protective immunity against Influenza. Key words: IgE, Influenza virus, Influenza virus vaccine INTRODUCTION Previous studies in our laboratory have investi-gated...