... PONDRÒ prediction of order and disorder and the observed sites of protease resistance and sensi-tivity, respectively [113].Summarizing, XPA is an illustrative example of theclass of hub proteins ... Successful completion of this task could lead to improved quality of the overalldata, shed light on the mechanisms of timing and regu-lation, indicate how global and local properties of complex macromolecular ... Iakoucheva3 and Vladimir N. Uversky1,41 Department of Biochemistry and Molecular Biology, and the Center for Computational Biology and Bioinformatics, Indiana UniversitySchool of Medicine,...