... individual diseases are the “prior questions,” the issues that drive the problem. If these questions were resolved, the burden of disease would shift toward non-communicable disease, the so-called ... disease will die within the rst month of life.(7) In the case of rheumatic heart disease one in ve will die by the age of 15 years, and almost 4 in 5 will be dead by the age of 25.(8)Christiaan ... B, Kumar, R.K. 2005. The global burden of congenital heart disease. Congenital Cardiology Today. 3(10):1-8.72. Hoffman JIE, Kaplan S. The incidence of congenital hear t disease. J Am Coll Cardiol...