Báo cáo Y học: The effect of amino-acid substitutions I112P,

Báo cáo Y học: The effect of amino-acid substitutions I112P, D147E and K152N in CYP11B2 on the catalytic activities of the enzyme pdf

... Eﬀect of I112P, D147E, K152N on CYP11B2 activity (Eur. J. Biochem. 269) 1127 The effect of amino-acid substitutions I112P, D147E and K152N in CYP11B2 on the catalytic activities of the enzyme Stephanie ... [17–19,41,42]. These stuc tures are mainly located in the C-terminal regions of CYP11B1 and CYP11B2. So far, the role of distinct...

Ngày tải lên : 24/03/2014, 03:21

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Báo cáo y học: "Different effect of exercise on left ventricular diastolic time and interventricular dyssynchrony in heart failure patients with and without left bundle branch block"

... test, interventricular dyssynchrony Introduction The introduction of cardiac resynchronization therapy has recently renewed the clinical interest in the analysis of specific phases of the cardiac ... reducing LV dyssynchrony and thereby liber- ating a further segment of the RR interval for diastole (24). Considering that direct evaluation of LV dyssynchrony is sti...

Ngày tải lên : 05/11/2012, 11:32

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Báo cáo Y học: Guanosine diphosphate-4-keto-6-deoxy-D-mannose reductase in the pathway for the synthesis of GDP-6-deoxy-D-talose in Actinobacillus actinomycetemcomitans potx

... GDP-4-keto-6-deoxy- D -mannose reductase and the stereoselectivity of the reduction deter- mines the direction of synthesis of these two 6-deoxyhex- oses. However, neither the gene encoding the biosynthesis of GDP-6-deoxy- D -talose ... hydrolyse them; they were then dried to remove the water and HCl. The pellets were converted into the corresponding D -(+)-2-octyl...

Ngày tải lên : 17/03/2014, 10:20

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Báo cáo Y học: A new siglec family member, siglec-10, is expressed in cells of the immune system and has signaling properties similar to CD33 docx

... phosphorylation by any of the kinases that were tested. In addition, a construct containing Y6 41 alone was not phosphorylated by any of the kinases, conﬁrming that Y6 41 is probably not a site for phosphorylation ... to the phosphorylation of the wild-type siglec tail by Lck and Jak3 kinases. By comparison, the mutation of the tyrosine at position 641 did not signiﬁ...

Ngày tải lên : 24/03/2014, 04:21

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Báo cáo Y học: Brassica napus soluble epoxide hydrolase (BNSEH1) Cloning and characterization of the recombinant enzyme expressed in Pichia pastoris docx

... concentration so the free concentration is actually lower. Addition of ethanol alone had only a minor effect on the enzyme activity while addition of dimethyl- sulfoxide caused almost 20% reduction in ... 5299 DISCUSSION The BNSEH1 was cloned and found to encode a protein of 318 amino acid residues. The recombinant enzyme was functional and readily detected by assa...

Ngày tải lên : 31/03/2014, 08:20

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Báo cáo y học: "Intrathecal siRNA against Toll-like receptor 4 reduces nociception in a rat model of neuropathic pain"

... play a role in neuropathic pain. Methodology/Principal Findings: In this study, we inves- tigated the role of TLR4 in a rat chronic constriction injury (CCI) model and explored the feasibility ... through inhibiting the activation of NF-κB p65 and production of proinflammatory cytokines (e.g., TNF-α and IL-1β). Conclusions/Significance: These findings suggest that...

Ngày tải lên : 25/10/2012, 11:48

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Báo cáo y học: "Low socio-economic status, smoking, mental stress and obesity predict obstructive symptoms in women, but only smoking also predicts subsequent experience of poor health"

... important role in the aetiology of asthma and that these hormones are influenced by obesity. Direct effects of regurgitation due to abdominal obesity and inflammatory effects on the bronchioles have ... possibility of gender specificity in the BMI effect on the development of asthma. They used longitudinal data from the National Population Health Survey...

Ngày tải lên : 31/10/2012, 15:34

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Báo cáo Y học: Agmatine oxidation by copper amine oxidase Biosynthesis and biochemical characterization of N-amidino-2-hydroxypyrrolidine pdf

... 1. Values of K i for N-amidino-2-hydroxypyrrolidine, agmatine, and clonidine binding to NOS-I, NOS-II, and trypsin. Enzyme K i ( M ) N-Amidino-2- hydroxypyrrolidine Agmatine Clonidine NOS-I (1.1 ... human enzyme was used instead. The confor- mations of the N-amidino-2-hydroxypyrrolidine in the enzyme: inhibitor complexes were obtained after 10 ps molecular dynamics. Ene r...

Ngày tải lên : 17/03/2014, 23:20

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Báo cáo y học: "A k2A-positive Klebsiella pneumoniae causes liver and brain abscess in a Saint Kitt’s ma"

... cephalosporins (cefazolin, cefotaxime, and cefepime), the fluoroquinolones (ciprofloxacin, levofloxacin), the aminoglycosides (amikacin, gentamicin, and tobra- mycin), meropenem, pipercillin/tazobactam ... serotype of K. pneumoniae is the second most common type of strain isolated from liver abscesses [8]. In conclusion, through culture methods and 16S rRNA sequencing,...

Ngày tải lên : 26/10/2012, 09:53

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Báo cáo y học: "A possible link between exercise-training adaptation and dehydroepiandrosterone sulfate- an oldest-old female study"

... 2006.09.10 The purpose of this study was to determine the association between the level of salivary dehydroepiandrosterone sulfate (DHEA-S) and the magnitude of adaptation to exercise training in insulin ... a role in functional recovery in hu- mans [17]. To determine the association of DHEA-S with exercise-training adaptation, the effect of 4 months of e...

Ngày tải lên : 31/10/2012, 16:49

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