... proteoglycan and laminin, but also process a number of cell-sur-face and soluble proteins, including receptors and cytokines such as inter-leukin-1b. The present work reviewed the role of neuroinflammatorymediators ... macrophages,suggesting that fractalkine is involved in neuron–microglia signalling [178]. In fact, this chemokineparticipates in leukocyte migration and in the activa-tion and chemoattraction of microglia into ... biologically active interleukin-1 beta by meprin B.Cytokine 31, 394–403.140 Pinteaux E, Inoue W, Schmidt L, Molina-Holgado F,Rothwell NJ & Luheshi GN (2007) Leptin inducesinterleukin-1beta release...