... inE 2A )/)may have resulted from the balanced mRNA(and probably protein) levels of caspase-8, which leadto activation of pro-caspase-9, causing formation of the active form of caspase-3, and of the ... 23977–23990.22 Nakayama M, Suzuki H, Yamamoto-Nagamatsu N,Barman HK, Kikuchi H, Takami Y, Toyonaga K,Yamashita K & Nakayama T (2007) HDAC2 controlsIgM H- and L-chain gene expressions via EBF1, Pax5,Ikaros, ... amount of activatedcaspase-3 itself as a result of decreased caspase-8 (andprobably caspase-9) activity, and the elevated protein(and also mRNA) levels of the inhibitors survivin andIAP2. As a...