Báo cáo Y học: Modelling of simple and complex calcium oscillations From single-cell responses to intercellular signalling pdf
Báo cáo Y học: Modelling of simple and complex calcium oscillations From single-cell responses to intercellular signalling pdf
... Springer,New York.Ó FEBS 2002 Modelling calcium oscillations (Eur. J. Biochem. 269) 1351REVIEW ARTICLE Modelling of simple and complex calcium oscillations From single-cell responses to intercellular signalling Stefan ... study of the phosphoinositide p athway, of which the hydrolysis of PIP2into IP3 and DAG is but a tiny part. A number of phosphoinositides linked b y kinases and phosphatases havebeen found to ... vb,j,netrate of binding of C a2+ to th e j-th class of Ca2+buffer (e.g. protein);vd, degradation of IP3(performed mainly by hydrolysis to inositol-1,4-bisphosphate or p hospho rylation to inositol-1,3,4,5-tetrakisphos-phate);...
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Tài liệu Báo cáo Y học: Thermostability of manganese- and iron-superoxide dismutases from Escherichia coli is determined by the characteristic position of a glutamine residue pdf
... manganese.Selectivity of the proteins for their metal cofactor has beendemonstrated in vivo [3] and although apoenzymes of eachtype of SOD may be reconstituted by the addition of metals,the resulting enzyme ... above.Assay for superoxide dismutase activityThe specific activity of SOD was measured spectrophoto-metrically by its inhibitory action on the superoxide-dependent reduction of cytochrome c by xanthine-xanthineoxidase ... bythe concerted effects of a combination of key residues.Further analysis of these and other mutant SODs iscurrently underway.ACKNOWLEDGEMENTSWe are indebted to G. Peplow, F. Yamakura and...
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Báo cáo y học: "Identification of clinical and simple laboratory variables predicting responsible gastrointestinal lesions in patients with iron deficiency anemia"
... defi-ciency anemia. The aim of our study was to investi-gate the incidence of GI pathological findings in symptomatic and asymptomatic patients with IDA and to identify the predictive factors for ... minimally 12 and maximally 60. The patients investigated previous smoking history, coronary artery disease, diabetes mellitus and malignancy history in their family. Statistical Analysis ... hungry and an -xiety, abdominal distension, nausea, vomiting, poor appetite and symptoms of gastroesophageal reflux. All patients were graded 1 to 5 for these symptoms. Dyspepsia score of patients...
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Báo cáo y học: "Use of chinese and western over-the-counter medications in Hong Kong"
... characteristics of populations who rely on community pharma-cists and Chinese medicine retailers as their main point of contact with the healthcare system. Analyzing the data from a Hong Kong survey (n ... community pharmacists work indepen-dently from medical doctors who often prescribe and dispense medications in a clinical setting. On the otherhand, patients often seek first line treatment from ... com-munity pharmacists [1]. Community pharmacists havelong been an underutilized part of the human resourcesin primary care [2,3] as a result of the interplay betweendemand, supply and organization...
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Báo cáo y học: "Characterization of N200 and P300: Selected Studies of the Event-Related Potential Salil H. Patel 1 and Pierre N. Azzam 2"
... SA, Brandt ME. Psychophysiology of N200/N400: A review and classification scheme. Advances in Psychophysiology 1991; 4:43-106. 4. Hoffman JE. Event-related potentials and automatic and controlled ... sensory auditory memory trace with increasing age [19]. The same phenomenon occurs in the very young, indicating the necessity of maturational changes for the complete efficiency of the auditory ... approximately 300 to 400 ms following stimulus presentation. Timing of this component may range widely, however, from 250 ms and extending to 900 ms, with amplitude varying from a minimum of 5 µV to...
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Báo cáo y học: "Comparison of Classical and Clozapine Treatment on Schizophrenia Using Positive and Negative Syndrome Scale of Schizophrenia (PANSS) and SPECT Imaging"
... reported that the efficacy of Clozapine is clinically significant on the negative symptomatology but is delayed compared to the efficacy on the other dimensions of symptomatology evaluated using the ... single-photon emission computed tomography and the Tower of london. Arch Gen Psychiatry, 1992; 49:943-958. 14. Kwon JS, McCarley RW, Hirayasu Y, Anderson JE, Fischer IA, Kikinis R, Jolesz FA, Shenton ... in winter and early spring, and viral infections in the mother during the second and third trimesters of gestation. A strong association between hypofrontality and negative symptoms of schizophrenia,...
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Báo cáo Y học: Ubiquitination of soluble and membrane-bound tyrosine hydroxylase and degradation of the soluble form ppt
... Ubiquitination of soluble and membrane-bound tyrosine hydroxylase and degradation of the soluble formAnne P. Døskeland and Torgeir FlatmarkDepartment of Biochemistry and Molecular Biology, University of ... sible contributions of labile a sparagineresidues to differences in regulatory properties of human and ratphenylalanine hydroxylase. In Chemistry and Biology of Pteridines and Folates 2001 (Parrak, ... (1997)Molecular characterization of disease related mutant forms of human phenylalanine hydroxylase and tyrosine hydroxylase. InChemistry and Biology of Pteridines and Folates (Pfleiderer,W.&Rokos,...
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Báo cáo Y học: Requirement of caspase and p38MAPK activation in zinc-induced apoptosis in human leukemia HL-60 cells potx
... thecytotoxicity induced by elevation of intracellular Zn level.The addition of extracellular Zn (at concentrations of up to 200 lM) to HL-60 cells did not cause cytotoxicity. However,cytotoxicity of ... 5%CO2atmosphere.Cytotoxicity of Py/Zn in HL-60 cellsThe cytotoxicity of Py/Zn in HL-60 cells was analyzedby colorimetric 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay with some ... induction of apoptosis was accompanied by activation of caspase and p38MAPK. Both a broad-spectrum inhibitor of caspase and an inhibitor of p38MAPKattenuated the induction of apoptosis by Zn....
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Báo cáo Y học: Effect of coenzymes and thyroid hormones on the dual activities of Xenopus cytosolic thyroid-hormone-binding protein (xCTBP) with aldehyde dehydrogenase activity potx
... Effect of coenzymes and thyroid hormones on the dual activities of Xenopuscytosolic thyroid-hormone-binding protein (xCTBP)with aldehyde dehydrogenase activityKiyoshi Yamauchi and Jun–ichiro ... T3-bindingactivity of xCTBP/xALDH1 was directly examined byphotoaffinity-labeling using intact Xenopus cells. Analyses of the cytosol obtained from the cell lines (KR and XL58) and the adult liver ... concentration, wouldpoorly modulate the enzyme activity of xCTBP/xALDH1.Keywords: cytosolic thyroid-hormone-binding protein;aldehyde dehydrogenase; retinoic acid synthesis; Xenopuslaevis.Hydrophobic molecules...
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Báo cáo Y học: Effect of ibuprofen and warfarin on the allosteric properties of haem– human serum albumin A spectroscopic study potx
... Ascenzi2 and Mauro Fasano31Department of Chemistry ‘IFM’, University of Torino, Italy;2Department of Biology, University ‘Roma Tre’, Rome, Italy;3Department of Structural and Functional Biology, ... modification, and renders potential toxins harmless by transporting them to disposal sites. HSA also accounts for most of theantioxidant capacity of human serum, either directly or bybinding and carrying ... absence and presence of ibuprofen and warfarin, haem binds to HSA mostly at the high affinity site and virtually no freehaem is present in solution (see [1,8,21], and present study).Values of the apparent...
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