Báo cáo Y học: Fluorescence study of the high pressure-induced denaturation of skeletal muscle actin pdf
Báo cáo Y học: Fluorescence study of the high pressure-induced denaturation of skeletal muscle actin pdf
... Fluorescence study of the high pressure-induced denaturation of skeletal muscle actin Yoshihide Ikeuchi1, Atsusi Suzuki2, Takayoshi Oota2, Kazuaki Hagiwara2, Ryuichi Tatsumi1, ... thermodynamicinformation about the behaviour of actin under pressure. The dissociation rate constants of nucleotides from actin molecules ( the decay curve of the intensity o f ¯uorescence of eATP ... to the dissociation of actin and myosinunder pressure. Then in situ observations were made bymonitoring the ¯uorescence of an eADP bound actin HMM (the products of myosin digested by trypsin)...
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Tài liệu Báo cáo Y học: Dinucleoside polyphosphates stimulate the primer independent synthesis of poly(A) catalyzed by yeast poly(A) polymerase ppt
... SpainNovel properties of the primer independent synthesis of poly(A), catalyzed by the yeast poly(A) polymerase arepresented. The commercial enzyme from yeast, in contrast totheenzymefromEscherichia ... catalyze the synthesis of a poly(A) chain in the absence of a primer [1]. In orderto explore whether the yeast enzyme also exhibited the same properties we assayed, in parallel, the activity of both ... independent synthesis of poly(A)In order to understand why dinucleoside polyphosphatesactivated the primer independent synthesis of poly(A), the effect of 0.01 mMGp4GorAp4A on the synthesis of poly(A)...
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Báo cáo Y học: Structural basis for the inhibitory efficacy of efavirenz (DMP-266), MSC194 and PNU142721 towards the HIV-1 RT K103N mutant doc
... aresuperimposed in the mutant NNIBP. The cyclopropyl-group of MSC194 and the methyl group of PNU142721partly overlap the trifluoromethyl group of Efavirenz.Furthermore, wing2 composed of the heterocyclic ... composed of the substituted phenyl ring of MSC194 and the fused ring-structure of PNU142721 overlap the less bulky cyclopropylgroup of Efavirenz. The overall similarity in binding mode of the inhibitorsto ... alue thanobtained by others [9]. T his may be due to the use of homopolymeric rC-dG template in the assay. The assayshows that PNU142721 is the most potent of the threetowards the K103N mutant...
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Tài liệu Báo cáo Y học: Kinetic study of sn-glycerol-1-phosphate dehydrogenase from the aerobic hyperthermophilic archaeon, Aeropyrum pernix K1 potx
... decreased dramatically,which seemed to be caused by irreversible denaturation of the enzyme. With the exception of the temperature-activity profile, the characteristics of the enzyme weredetermined ... specificity and enzyme activity The substrate specificity of Gro1P dehydrogenase wasexamined using the purified enzyme. No activity w asobserved t oward glyceraldehyde phosphate, Gro3P,glycer-ol-2-phosphate ... The high growth temperature of A. pernixmay be linked to the higher optimum activity tempera-ture of its Gro1P dehydrogenase [24]. The half-life of activity was 30 min at the maximal activity...
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Báo cáo Y học: Structural study on lipid A and the O-specific polysaccharide of the lipopolysaccharide from a clinical isolate of Bacteroides vulgatus from a patient with Crohn’s disease ppt
... 2)substitutions of GlcNIand an acyoxyacyl substitution atN2-GlcNII. Cleavage F indicated the chain length of the fatty acid on the acyoxyacyl group to be mainly 15,confirming the result of the compositional ... in the LPS must be responsible for this weak activity.Structure of OPS moiety in LPSTo analyze the structure of the OPS moiety, the hydrophilicproducts from the acetic acid hydrolysate of ... spectrum revealed the presence of a monophosphoryl lipid A (Fig. 3A). The molecular mass heterogeneity can be explained by the degree of acylation and the chain length of the fatty acid. The ions at...
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Báo cáo y học: "Special considerations in the treatment of patients with bipolar disorder and medical co-morbidities"
... risk of type 2 diabetes mellitus, dyslipidemia,hypertension, stroke, ischemic heart disease and earlymortality [6-9]. The authors concluded that the preva-lence of obesity in this study of outpatients ... diagnosis of general medical conditions may bedelayed. As the physician with the most (and often the only) contact with these patients, psychiatrists need to bevigilant in detecting early signs ... [40]. Further, many of the medications that treat bipolar disorder may have car-diac side effects or toxicity. Underlying cardiac diseasemay also affect the pharmacokinetics of psychotropics.Congestive...
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Báo cáo y học: "Mirror-Image Arachnoid Cysts in a Pair of Monozygotic Twins: A Case Report and Review of the Literature"
... pathogenesis of AC. The findings in our case indicate that early neuroimaging is mandatory in the counterpart of the sympto-matic patient with AC, irrespective of the absence of symptoms. Key words: ... an uneventful pregnancy of a healthy 24-year-old mother. They have no family history of genetic diseases. Both had Apgar scores of 9/9 at 1 minute and 9/9 at 5 minutes. The placenta was examined ... that it is mandatory to monitor the counterpart of the symptomatic patient with AC as early as possible, irrespective of the absence of symptoms. Conflict of Interest The authors have declared...
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Báo cáo y học: "Clinical Strategy for the Management of Solid Pseudopapillary Tumor of the Pancreas: Aggressive or Less"
... of body or tail of the pancreas. For tumors of SPT located in the neck and body of the pancreas, resection of the mid-portion of the pancreas and the mass with preserving the rim of the head ... analysis of sol-id-pseudopapillary tumor of the pancreas: report of 15 cases. Hepatobilliary Pancreat Dis Int. 2008;7(2):196-200. 10. Yu CC, Yeh CN, Hwang TL, Jan YY. Clinicopathological study ... result in the uncertainty of the strategy for its treatment. While further delineati n g the clinicopathological and radiological features, and summarizing the surgical therapy strategy of this...
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Báo cáo y học: "Why are some children with early onset of asthma getting better over the years" -aneuploid-prostate-cancer-cells-after-tmz-tmz-bioshuttle-treatment.html#post143974
... PHC data of the statements made by the mid-wife in her records of the check-up of the mothers during the pregnancy (17). In the follow-up at the age of seven, n= 191 children of the defined ... (19). Interestingly, the exposition for pet animals tended to be higher in the NA cases, which may support the hygiene hypothesis, but may also be due to higher sensitivity in the A group. Previous ... the same as those identified clinically. In a study of children between 1 – 2 years of age the pa-rental questionnaire was only able to identify 54% of the children with a medical record of...
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Báo cáo y học: "Comparative study of control selection in a national population -based case-control study: Estimating risk of smoking on cancer deaths in Chinese men"
... policy making when an answer is needed a short time. The purpose of this study was to apply the basic principles of a population-based case-control study to assess the validation of the novel ... indicating there is no obvious disagreement in smoking history reported by proxy or by self-report. In this study, we attempt to apply the equiva-lence approach to assess the consistency of different ... Information obtained from the spouse on the hus-band’s smoking habits was highly consistent with information provided directly by the husband. In this study, the very similar trends exit between...
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