... suggested to be linked toearly stages of PD pathogenesis [26]. Interestingly, in our model, dopamine induces an increase of the actinbundles regulator fascin 1 [27] and discordant changes of two calcium-dependent, ... of ββ-Actinα-SynucleinFig. 1. Relative expression of a-synuclein in b-gal and a-syn cells in response to dopamine (DA) treatment. Results are indicated as thefold of induction relative to expression observed in ... of four proteins [stathmin 1, glutathione S-transferase(GST)p, Ran 1 binding protein and C1q binding pro-tein], related to cell signaling, apoptosis and cytoskele-ton regulation (Fig. 2, insets;...