... 2578–2590 ª 2005 FEBS
Calpain 1 titin interactions concentrate calpain 1 in the
Z-band edges and in the N2-line region within the skeletal
myofibril
Fabrice Raynaud
1
, Eric Fernandez
2
, Gerald Coulis
2
, ... Thus,
according to these and previous results [20, 21] , titin
appears to be a calpain carrier that concentrates cal-
pain 1 and 3 in...
... Heath JK (19 92) Involvement
of AP1 and PEA3 binding sites in the regulation of
murine tissue inhibitor of metalloproteinases -1 (TIMP-
1) transcription. Biochim Biophys Acta 11 71, 41 55.
38 Ulisse ... &
Narumiya S (19 96) Rhotekin, a new putative target for
Rho bearing homology to a serine ⁄ threonine kinase,
PKN, and rhophilin in the rho-binding domain. J Biol
Chem 2 71,...
... 7.4, containing 13 5 mm NaCl) supple-
mented with a mixture of protease inhibitors (10 0 lgÆmL
)1
PMSF, 2 lgÆmL
)1
leupeptin, 1 lgÆmL
)1
pepstatin A, and
1 lgÆmL
)1
p-toluenesulfonyl-l-arginine methyl ... for the PDGF
and EGF receptor protein-tyrosine kinases in vivo and
in vitro. Cell 57, 11 09 11 22.
18 Holgado-Madruga M, Emlet DR, Moscatello DK,
Godwin AK & W...
... 5¢-TCA
AAATTGGTGTGAATGACGAGAAAC-3¢ and P598. The
resulting F11E6 .1: :mCherry product was coinjected into N2
at 20 ngÆlL
)1
with pRF4[Rol-6
D
] at 10 0 ng ÆlL
)1
. kxEx148
[F11E6 .1: :mCherry; rol-6(su1006)
D
] was used in the ... pyr -1( RNAi)
f
10 0 73
umps -1( RNAi); pyr -1( cu8)
f
00 0 31
umps -1( zu456); pyr -1( cu8)
m
00 0 40
umps -1( zu456); R12E2 .11 (RNAi)
f
10 0 0 0...
... regarding the molecular mechanisms underlying
the detrimental role of the enzyme in ischemic brain
injury [ 31, 32]. Indeed, although we know in part the
mechanisms activated by PARP -1 and triggering
neurotoxicity, ... Metab 19 , 819 –834.
17 Iadecola C & Alexander M (20 01) Cerebral ischemia
and in ammation. Curr Opin Neurol 14 , 89–94.
18 Wang X & Feuerstein G...
... relatively
low, the N-terminal region (aN–a1), the aF–aG region
and the C-terminal region (a4–a5) were well conserved
between GOA -1 and Ga
o
[ 31, 32]. The five regions of
the Ga-subunit involved in receptor ... GTPcS in GOA -1. The
IC
50
value of the displacement of GTPcS by GDP was
3 · 10
)6
m with 0.2 mm atropine, and 10
)4
m without
atropine in the p...
... activation, resulting in a transfer of
leukocyte integrins into a high affinity conformation.
The integrins now allow the leukocytes to adhere firmly
to the endothelium by interactions with intercellular
adhesion ... small
GTPases, reactive oxygen species and protein kinases,
are involved in these signaling events.
doi: 10 .11 11/ j .17 42-4658.2006.05436.x
FEBS Journal 273 (2006...