Báo cáo khoa học: The multifarious short-term regulation of

Báo cáo khoa học: The multifarious short-term regulation of ammonium assimilation of Escherichia coli: dissection using an in silico replica pdf

... 1983 The multifarious short-term regulation of ammonium assimilation of Escherichia coli: dissection using an in silico replica Frank J. Bruggeman 1 , Fred C. Boogerd 1 and Hans V. Westerhoff 1,2,3 1 ... the dynamics of the network in terms of a set of nonlinear ordinary differential equations. Mass-ﬂow description of the UTase subnetwork and bi...

Ngày tải lên : 23/03/2014, 13:20

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Tài liệu Báo cáo khoa học: The cellulosomes from Clostridium cellulolyticum Identiﬁcation of new components and synergies between complexes ppt

... new proteins is based on the GH family of the catalytic module and the modular organization of the protein, or on the identity of the catalytic domain with another characterized protein (see text). Protein ... using the MALDI-TOF technique, except for the proteins 6, 7a and 7b, and 10 which were identiﬁed using the MS ⁄ MS technique. The modular structure of ne...

Ngày tải lên : 18/02/2014, 08:20

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Báo cáo khoa học: The 2-oxoacid dehydrogenase multi-enzyme complex of the archaeon Thermoplasma acidophilum ) recombinant expression, assembly and characterization docx

... machinery is able to rec- ognize the lipoyl-domain of the Thermoplasma E2 enzyme, the target lysine of which is ﬂanked by D and V residues, as it is in the E2 protein of the E. coli OGDHC and of ... recombinant proteins to assemble into an a 2 b 2 enzyme that catalyzes the decarboxylation of the branched-chain 2-oxoacids and pyruvate [14]. In the current paper,...

Ngày tải lên : 16/03/2014, 05:20

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Báo cáo khoa học: The retinoid-X receptor ortholog, ultraspiracle, binds with nanomolar afﬁnity to an endogenous morphogenetic ligand pptx

... 5 which forms one of the internal borders of the ligand-binding pocket. The side chain of W318 itself is directed into the ligand-binding pocket. Thus, the trypto- phan is in a position to potentially ... farnesoate binding is different to than that upon JH III binding. We previously tagged the transcription-modulating AF2 group of the ligand-binding domain using a p...

Ngày tải lên : 16/03/2014, 12:20

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Báo cáo khoa học: The CRIPTO/FRL-1/CRYPTIC (CFC) domain of human Cripto Functional and structural insights through disulﬁde structure analysis docx

... 2A1), and therefore that the CFC domain is sufﬁcient for the interaction of Cripto with ALK4. To verify the role of the CFC domain in ALK4 binding, we analyzed the effects of point mutations in the ... mature human Cripto contains 12 cysteine residues, six in the EGF domain and six in the CFC domain. To test whether the CFC domain could retain its function inde...

Ngày tải lên : 23/03/2014, 21:20

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Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf

... proteins with the promoter. E2F4 binding during the cell cycle coincides with the binding of p107 or p130 [61,85]. Another E2F site distal to the E2F ⁄ CDE acts as an activating element binding ... composed of p130, E2F4 ⁄ 5 and DP1 ⁄ 2 and a module containing the MuvB proteins Lin-37, Lin-52, Lin-54 and chromatin- associated Lin-9 and Lin-53 ⁄ RBBP4 ⁄ RbAp48. Furthermore, A-M...

Ngày tải lên : 16/02/2014, 09:20

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Tài liệu Báo cáo khoa học: The subtle side to hypoxia inducible factor (HIFa) regulation pdf

... MAPK. Introduction Spurred-on by the discovery of their involvement in the pathophysiology of many disease states including cerebral and pulmonary ischemia, cancer tumourigenesis and malignancy [1], the bHLH-PAS domain-containing hypoxia-inducible ... In contrast to these ﬁndings, the two cytokines were reported to act in the same manner to increase transcription of HIF1...

Ngày tải lên : 20/02/2014, 23:20

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Báo cáo khoa học: The catalysis of the SARS 3C-like protease is under extensive regulation by its extra domain doc

... middle of the dimeric enzyme. In fact in the core region, only two direct in- termonomer contacts exist, namely between Glu290 of one protomer and Arg4 of another. Indeed, the importance of the ... regulating the catalytic machinery. It would be of signiﬁcant interest in the future to introduce the mutations into viral infectious clones to test whether these...

Ngày tải lên : 07/03/2014, 12:20

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Báo cáo khoa học: The sigma factors of Mycobacterium tuberculosis: regulation of the regulators potx

... C-terminal domain, possibly involved in sensing an in vivo stimulus for the release of r K and an intracellular N-terminal domain involved in interaction with r K . Certain mutations in M. ... factor- a-a, interleukin-1b, interleukin-6 and interferon-c in the lungs of the infected animal [51]. The attenuation of the sigC mutant may result from dysregulation of...

Ngày tải lên : 15/03/2014, 09:20

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Báo cáo khoa học: Gonadotropin-releasing hormone: regulation of the GnRH gene pot

... have therefore varied according to the time at which the animals were killed, the dose and duration of estrogen treatment, and the region of the brain analyzed [75]. During the estrous cycle, the ... Phosphorylation of Oct-1 inhibits the Oct-1 binding activity [125], thus the repression of GnRH-I gene expression [31]. Retinoic acid (RA) The role of vitamin A and...

Ngày tải lên : 16/03/2014, 04:20

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