... mutation, thiscould either mask or enhance the clinical manifestation of the disease [6,26]. Although the individuals with this mutation have remained asymptomatic, the analogousmutations in glutaryl-CoA ... individual depending on the functionaloverlap of VLCAD, LCAD, MCAD and SCAD, the efficiency of the chaperonin-aided folding, the effi-ciency of the detoxification of accumulated intermedi-ates, and avoidance ... protein. The catalytic competence of the enzyme is in any case not greatly affected, suggesting that anyFAD binding impairment cannot be the primary dele-terious effect of this mutation. As the...