Báo cáo khoa học: Recruitment of coregulator complexes to the b-globin gene locus by TFII-I and upstream stimulatory factor doc

Báo cáo khoa học: Recruitment of transcription complexes to the b-globin locus control region and transcription of hypersensitive site 3 prior to erythroid differentiation of murine embryonic stem cells docx

Báo cáo khoa học: Recruitment of transcription complexes to the b-globin locus control region and transcription of hypersensitive site 3 prior to erythroid differentiation of murine embryonic stem cells docx

... analyzed recruitment of factors to the a-globin gene locus dur- ing the differentiation of erythroid cells. The regula- tory elements located upstream of the a-globin genes also appear to initiate the ... activation of the gene locus. However, in contrast to the b-globin LCR and the VpreB1 and k5 gene locus, the a-globin regulatory ele- men...
Ngày tải lên : 07/03/2014, 12:20
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Báo cáo khoa học: Recruitment of coregulator complexes to the b-globin gene locus by TFII-I and upstream stimulatory factor doc

Báo cáo khoa học: Recruitment of coregulator complexes to the b-globin gene locus by TFII-I and upstream stimulatory factor doc

... Recruitment of coregulator complexes to the b-globin gene locus by TFII-I and upstream stimulatory factor Valerie J. Crusselle-Davis, Zhuo Zhou, Archana ... to the b-globin gene. Together, these data demonstrate that the antagonistic activities of upstream stimula- tory factor and TFII-I on b-globin gene expression are mediated at least in...
Ngày tải lên : 23/03/2014, 07:20
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Báo cáo khoa học: Loss of sense transgene-induced post-transcriptional gene silencing by sequential introduction of the same transgene sequences in tobacco pot

Báo cáo khoa học: Loss of sense transgene-induced post-transcriptional gene silencing by sequential introduction of the same transgene sequences in tobacco pot

... information), and the 5¢-termini of the NtFAD3 transgene cDNAs were distributed in the same region of the transgene sequences, suggesting that the NtFAD3 transgene was transcribed under the control of the same ... for the endogene). In contrast, the level of nuclear transcripts of the NtFAD3 transgene was reduced to 0.75 ± 0.20 of those of S44 plants (mea...
Ngày tải lên : 22/03/2014, 21:20
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Báo cáo khóa học: Characterization of presenilin complexes from mouse and human brain using Blue Native gel electrophoresis reveals high expression in embryonic brain and minimal change in complex mobility with pathogenic presenilin mutations pptx

Báo cáo khóa học: Characterization of presenilin complexes from mouse and human brain using Blue Native gel electrophoresis reveals high expression in embryonic brain and minimal change in complex mobility with pathogenic presenilin mutations pptx

... available. To analyse further the composition of the PS1 complex, samples with high expression of PS1 complex were selected for further study. BN/PAGE gel bands corresponding to the region of PS1 complex ... [19] to analyse further and characterize endo- genous native complexes from mouse and human brain tissue and from the neuroblastoma line SH-SY5Y (SY5Y). Experi...
Ngày tải lên : 16/03/2014, 16:20
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Báo cáo khoa học: Modeled ligand-protein complexes elucidate the origin of substrate specificity and provide insight into catalytic mechanisms of phenylalanine hydroxylase and tyrosine hydroxylase pptx

Báo cáo khoa học: Modeled ligand-protein complexes elucidate the origin of substrate specificity and provide insight into catalytic mechanisms of phenylalanine hydroxylase and tyrosine hydroxylase pptx

... binding to the catalytic domains of PAH and TH Docking of the native cosubstrate BH 4 into the crystal structure of the PAH catalytic domain yielded a total of 286 conformations. Out of these, ... displayed the expected coordination of the tyrosine aromatic ring towards the iron atom. However, the hydroxyl group of the aromatic ring was placed trans to Hi...
Ngày tải lên : 31/03/2014, 07:20
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 Báo cáo khoa học: "Effect of intern’s consecutive work hours on safety, medical education and professionalism"

Báo cáo khoa học: "Effect of intern’s consecutive work hours on safety, medical education and professionalism"

... hand-offs offset the reduced errors associated with better-rested care providers? As noted by the authors, their intervention took place in a system that was designed to minimize the impact of ... calculated to be 80%, not 90%. In addition, there is one error in the description of the limitations that we would like to point out. Dr Sarani and Dr Alarcon note: “There we...
Ngày tải lên : 25/10/2012, 10:45
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Tài liệu Báo cáo khoa học: Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells pdf

Tài liệu Báo cáo khoa học: Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells pdf

... coadministered (Fig. 4C). Taken together, these results indicate that the location of the protective action of oleate was upstream of ER stress activation. Whether the protection offered by oleate was specific for ... Interestingly, the interruption of TAG synthe- sis preceded the appearance of toxic effects, supporting the notion that it constitutes the initiating...
Ngày tải lên : 14/02/2014, 22:20
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Tài liệu Báo cáo khoa học: Kinetics of dextran-independent a-(1 fi 3)-glucan synthesis by Streptococcus sobrinus glucosyltransferase I pdf

Tài liệu Báo cáo khoa học: Kinetics of dextran-independent a-(1 fi 3)-glucan synthesis by Streptococcus sobrinus glucosyltransferase I pdf

... to only one acceptor molecule until the release of the final product. Another mechanism is suggested by Mooser et al. on the basis of the identification of the active site and the similarity with ... addition, the kinetics of the acceptor reactions appeared to be similar between GS and GSGB. Kinetic simulation of GTF glucan synthesis To explain the time c...
Ngày tải lên : 14/02/2014, 22:20
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Tài liệu Báo cáo khoa học: Use of hydrostatic pressure to produce ‘native’ monomers of yeast enolase ppt

Tài liệu Báo cáo khoa học: Use of hydrostatic pressure to produce ‘native’ monomers of yeast enolase ppt

... helices in the large domain and two b-strands in the small domain. The active site is at the bottom of the barrel and is totally Correspondence to M. J. Kornblatt, Department of Chemistry and Biochemistry, ... 251, 775– 780]. The UV spectra of the high pressure forms of the Mg 2+ - and apo-forms of enolase are identical and distinct from the spectrum o...
Ngày tải lên : 19/02/2014, 16:20
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Tài liệu Báo cáo khoa học: Cleavage of nonphenolic b-1 diarylpropane lignin model dimers by manganese peroxidase from Phanerochaete chrysosporium Evidence for a hydrogen abstraction mechanism docx

Tài liệu Báo cáo khoa học: Cleavage of nonphenolic b-1 diarylpropane lignin model dimers by manganese peroxidase from Phanerochaete chrysosporium Evidence for a hydrogen abstraction mechanism docx

... 4-methoxyacetophenone (III) (Table 2). The percentage of 18 O incorporated was estima- ted by the ratio of the M + /(M + +2)peaksinthemass spectrum of the products. Neither the diarylpropane (I) nor the ... detectable amount of the a-keto diarylpropane (X) was produced in the absence of Tween 80 (Table 1). To determine possible pathways for the oxidation of...
Ngày tải lên : 20/02/2014, 23:20
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