Báo cáo khoa học: Effect of mutations in the b5–b7 loop on the structure and properties of human small heat shock protein HSP22 (HspB8, H11) pptx
Báo cáo khoa học: Carbohydrate binding sites in Candida albicans exo-b-1,3-glucanase and the role of the Phe-Phe ‘clamp’ at the active site entrance ppt
... subclone the mutation-contain-ing pFOX fragments into vector pGSB1, a pUC19 deriva-tive containing the complete EXG ORF. The entire ORFscontaining each mutation were then cloned into the SnaBIsite ... identified (three in the active site and two on the outside of the protein) .DiscussionExamination of the previously determined crystalstructures of native and inhibited forms of Exg fromC. albicans ... b-1,3-glucanpolymers. The nature of the aromatic residues in the two triads might then be reflecting the different func-tional constraints for the two proteins: Exg requiringprecise positioning of laminarin substrate...
- 13
- 498
- 0
Báo cáo khoa học: "Enhancing Language Models in Statistical Machine Translation with Backward N-grams and Mutual Information Triggers" ppt
... score of the F+M hypothesis -26.67. This couldbe the reason why the baseline selects the word“was” instead of “is”. As can be seen, there is an-other “is” in the preceding context of the word ... the succeeding context according toPb(wm1) =mi=1P (wi|wmi+1) ≈mi=1P (wi|wi+n−1i+1) (2)3.1 TrainingFor the convenience of training, we invert the or-der in each sentence in the ... P(e1)P(e2)P(R(e2)L(e1))P(R(e2))P(L(e1))(11)Figure 2: Integrating the backward language model intoa standard phrase-based decoder.segment. This extension on the target side is simi-lar to the monotone combination of Eq. (9) in that anewly...
- 10
- 415
- 0
Báo cáo khoa học: Fully active QAE isoform confers thermal hysteresis activity on a defective SP isoform of type III antifreeze protein docx
... imply that the large amount of the SP isoform contained in the body fluid makes asignificant contribution to ice growth inhibition with the help of the active isoform, thereby enabling the host ... Repeated binding of AFP to the prismplane and the generation of a smaller ice nucleus causesuccessive stacking of hexagonal ice plates on the basalplane, leading to the formation of an ice ... among the isoforms, which affects the observed TH value [8].Thus, the characterization of such isoforms and theircooperative effects on antifreeze activity will aid in ourunderstanding of the...
- 9
- 289
- 0
Tài liệu Báo cáo khoa học: Effect of deletion of the DNase I hypersensitive sites on the transcription of chicken Ig-b gene and on the maintenance of active chromatin state in the Ig-b locus docx
... was introduced into DT40cells. Ig-b gene expression, acetylation of H3 and H4histones, and the remaining DHSs in the deleted cellswere examined to determine the roles of these DHSs on the ... regions, and each of these regions was dele-ted in DT40 cells. The roles of the DHSs on Ig-b geneexpression and the maintenance of active chromatinstate in the Ig-b locus were examined in the dele-tion ... transcription of Ig-b gene and on the mainten-ance of the active chromatin state.ResultsGeneration of DT40/Cre cells with a long deletion in one allele of the Ig-b locusTo genetically examine the...
- 11
- 638
- 0
Tài liệu Báo cáo khoa học: "Effect of Cross-Language IR in Bilingual Lexicon Acquisition from Comparable Corpora" pot
... measured, and their curves against the changes of Ld are shown in Figure 2. Let DP„f denote the set of reference article pairs within the range of dates, the precise definitions of the precision and ... texts in ac-quisition of bilingual term correspondences.4.3.2 Rates of Containing Correct BilingualTerm PairsNext, we evaluate the following rate of containingcorrect bilingual term correspondences:{TP(tE) ... 97.43228.9837.7estimated. In the second approach, on the otherhand, as described in the previous section for the case of acquisition from (pseudo-) parallel cor-pora, the candidates of bilingual term pairs...
- 8
- 477
- 0
Báo cáo khoa học: Effect of priming on activation and localization of phospholipase D-1 in human neutrophils potx
... OÀ2 and PLD activationSelective pharmacological inhibitors were used to assess the role of PI3-kinase and ARF proteins on the activation of PLD. As illustrated in Fig. 3A,B, the PI3-kinaseinhibitor ... with the levels observed with TNFa or fMLP alone (Fig. 2B,C)with > 90% of the [3H]PtdBut accumulating within the first5 min of stimulation. Effect of PI3-kinase and ARF inhibitors on OÀ2 and PLD ... burst. However, the repertoire of PLD isoforms present in these primary cells, the precisemechanism of activation, and the impact of cell priming on PLD activity and localization remain poorly defined.RT-PCR...
- 10
- 468
- 0
Báo cáo khoa học: " Effect of the medical emergency team on long-term mortality following major surgery"
... combination of a potent quinolone combined with clindamycin. This strategyis commonly followed in our facility for infection of unknownorigin and generally corresponds to the guidelines of the ... (29%), and head (18%). Two-thirds of patients had combined injuriesto the thorax (for instance, pneumo-/hemopneumothorax),including intrapulmonary contusions and lesioning, and frac-tures of the ... carbapenems, amikacin, and quinolonesonly, MRSA, sensitive to fosfomycin, rifampicin, linezolid and glycopeptides only, and S. maltophilia, sensitive to ofloxacinonly (Figure 4).Anti-infective therapyAll...
- 9
- 761
- 0
Báo cáo khoa học: "Effect of intern’s consecutive work hours on safety, medical education and professionalism"
... descriptions thatappeared in our recent Journal Club review [1] of theirstudies examining the effect of reducing interns work hours in the intensive care unit [2,3].Our statement that “interns in the ... rapidly increases after 16 hours of sustainedwakefulness, a finding reflected in the twofold increase in interns’ attentional failures after they had been working formore than 16 hours on the traditional ... noted by the authors, their intervention tookplace in a system that was designed to minimize the impact of hand-offs, which by definition occurred more frequently in the intervention schedule....
- 3
- 514
- 0
Tài liệu Báo cáo khoa học: An alternative isomerohydrolase in the retinal Muller cells of a cone-dominant species doc
... liposomes con-taining atRE (A), liposomes containing atRE in the presence of 1mM bipyridine (B) and liposomes containing atRE, in the presence of 1 mM bipyridine and 6 mM FeSO4(C). The generated ... expressed in ganglion cells might contribute toproviding chromophore to melanopsin to maintaintheir light sensitivities. The expression and function of RPE65c in other cell types in the retina remains ... thetase to esterify the 13cROL generated in the reac-tion. Therefore, 13cROL is accumulated in the absence of LRAT in the reaction (Fig. S3B).Under the in vitro assay conditions of the...
- 14
- 753
- 0
Tài liệu Báo cáo khoa học: TEC family kinases in health and disease – loss-of-function of BTK and ITK and the gain-of-function fusions ITK–SYK and BTK–SYK pptx
... 1. Structure of PH, SH2 and kinase domains of BTK with color-ing of residues affected by missense mutations. Top left: locations of the missense mutation in the BTK PH domain; arginine 28 is in dark ... pre-sumably secondary to the strong in uence of prolines on peptide folding [21]. Thus, proline is a rigid aminoacid creating a fixed kink in a protein chain.Similar to the situation in many other genes, ... dramaticallyinduces transcription of the ITK gene and is key for the productive infection of HIV in these cells. Accord-ingly, the inhibition of ITK activity compromises HIVinfection, gene expression and...
- 10
- 926
- 0
Từ khóa: chuyên đề điện xoay chiều theo dạngNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namBiện pháp quản lý hoạt động dạy hát xoan trong trường trung học cơ sở huyện lâm thao, phú thọGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longNghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngTìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXChuong 2 nhận dạng rui roQuản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Tăng trưởng tín dụng hộ sản xuất nông nghiệp tại Ngân hàng Nông nghiệp và Phát triển nông thôn Việt Nam chi nhánh tỉnh Bắc Giang (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtBÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIĐổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namTÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ