... protein, and correctsequence predictions in two proteins, one of 2153 residues (229 kDa).AbbreviationsBCA, bovine carbonic anhydrase; CAD, collisionally-activated dissociation; ECD, electron-capture ... indiscriminate protein backbonecleavages. For example, 250 of the 258 inter-residuebonds could be cleaved (as assigned by the terminus-containing ions c, z., a., b and y) in bovine carbonicanhydrase ... ª 2007 The Authors Journal compilation ª 2007 FEBSdestroying information on their backbone location.However, the energetic (‘nonergodic’) dissociation of ECD is localized on the backbone, with...