Báo cáo khoa học: Systems biology: model based evaluation and comparison of potential explanations for given biological data pot
Báo cáo khoa học: Systems biology: model based evaluation and comparison of potential explanations for given biological data pot
... FEBS 921MINIREVIEW Systems biology: model based evaluation and comparison of potential explanations for given biological data Gunnar Cedersund1 and Jacob Roll21Department of Cell Biology, Linko¨ping ... some of the most central available analysis tools. Thefocus is on the evaluation and comparison of given explanations for a given set of experimental data and prior knowledge. Three types of meth-ods ... (a) for evaluation of whether a given model is sufficientlyable to describe the given data to be nonrejectable; (b) for evaluation of whether a slightly superior model is significantly better; and...
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Báo cáo khoa học: "Text Summarization Model based on Maximum Coverage Problem and its Variant" pot
... aconstraint of knapsack form. Filatova and Hatzi-vassiloglou (2004) pointed out that text summa-rization can be formalized by MCKP.The performance of the method depends on howto represent words and ... proposed model and the model proposed by Yih et al. (2007).7845 Experiments and Discussion5.1 Experimental SettingWe conducted experiments on the dataset of DUC’04 (2004) with settings of task ... of the 12th Conference of the European Chapter of the ACL, pages 781–789,Athens, Greece, 30 March – 3 April 2009.c2009 Association for Computational LinguisticsText Summarization Model based...
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Báo cáo khoa học: Systems biology: experimental design Clemens Kreutz and Jens Timmer docx
... definitions of the investigated hypoth-eses and the scope of the study are crucial. Also, anoverview of numerical optimization of designs for thepurpose of parameter estimation and for model discri-mination ... measurements and the pro-ceeding level of knowledge in cell biology allows theapplication of mathematical modeling approaches for testing and validation of hypotheses and for theprediction of new ... basis of experimental data, which model is the most appropriate [88–90].The accordance of the data and the model is exam-ined by evaluation of the maximum likelihood functionqðyj^pðMÞÞ for...
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Báo cáo khoa học: Systems biology: parameter estimation for biochemical models ppt
... Riel NAW (2006) Dynamic modelling and analysis of biochemical networks: mechanism -based models and model- based experiments. Brief Bioinform 7, 364–374.Supporting informationThe following supplementary ... deterministic model in the form of a mathematical function -based model is available, such as a system of differential and algebraic equations. For example, in the case of a bio-chemical process, hypotheses ... determined given a data set that is possibly sparse and noisy. Thatthis part of model fitting should not be underestimatedis shown by Gutenkunst et al. [7]. For all 17 systems biology models that...
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Báo cáo khoa học: "Validating the web-based evaluation of NLG systems" potx
... problem (Scott and Moore,2007): Task -based evaluations with human experi-mental subjects are time-consuming and expensive, and corpus -based evaluations of NLG systems areproblematic because a ... 374vs.n = 91), and offers other oppor-tunities for more fine-grained analysis as well. Wetake this as an empirical validation of the Internet- based evaluation of GIVE, and propose that it ... Proceedings of the ACL-IJCNLP 2009 Conference Short Papers, pages 301–304,Suntec, Singapore, 4 August 2009.c2009 ACL and AFNLPValidating the web -based evaluation of NLG systems Alexander KollerSaarland...
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Báo cáo khoa học: "a Topic-Model based approach for update summarization" potx
... available and, the more features it has, the more it is af-fected by the sparsity of the training data. 3 DualSum3.1 Model FormulationThe input for DUALSUM is a set of pairs of collec-tions of documents ... arethe average of five runs for all the baselines and for DUALSUM. DUALSUM outperforms two of the baselines in all three ROUGE metrics, and italso outperforms TOPICSUMBon two of the threemetrics.The ... words, a distribution of document-specific words or a distribution of the core content of a given cluster. BAYESSUM(Daum´e and Marcu, 2006) and the Special Words and Background model (Chemudugunta...
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Báo cáo khoa học: Intermodule cooperativity in the structure and dynamics of consecutive complement control modules in human C1r Structural biology docx
... Zolta´nGa´spa´ri and Luka´sˇZˇı´dek for their help in the interpretation of relaxation data and for their guidance when performing RSDM.We also thank A. K. Fu¨ze´ry for critical reading of themanuscript. ... 300 and 320 K at pH 4.0.Fig. S11. Set of HSQC spectra of CCP1CCP2 (#2) col-lected at 300 and 315 K at pH7.0.Fig. S12. Overlay of HSQC spectra collected at 300 K of single CCP1 and CCP2 and of ... mainly theb-strands. The loops between strands B and C, knownas the ‘hypervariable loop‘, D and E, E and F, F and G, and G and H are particularly tolerant of longerinsertions [19]. In multimodular...
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Báo cáo khoa học: "Designing a Task-Based Evaluation Method ology for a Spoken Machine Translation System" pot
... communication requires new evaluation criteria and metrics based on goal complexity and the speaker's prioritization of goals. 1 Introduction Task -based evaluations for spoken language sys- ... rather than whether they are achieved. 2 Goals of a Task -Based Evaluation Methodology for an MT System The goal of a task -based evaluation for an MT system is to convey whether speakers' ... distinction of goals based on subgoal com- plexity, (2) distinction of goals based on the speaker's prioritization, and (3) distinction of goals based on domain. 3 Prioritization of Goals...
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Tài liệu Báo cáo khoa học: Catabolite repression in Escherichia coli – a comparison of modelling approaches docx
... attributes for the two models. It follows a systematic comparison of both models with respect to the model structure, model validation and model prediction. Model structure – reasonableapplication of ... that model validation and acritical evaluation of modelling, and also of experimen-tal results, are of particular importance. This includesthe careful selection of biological experiments and experimental ... themethod of modular modeling is that the granularity of the submodels can easily be adjusted to the objective of the model and to the level of biological knowledgethat is incorporated in the model. Phosphoenolpyruvate⁄pyruvate...
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Tài liệu Báo cáo khoa học: Peptides corresponding to helices 5 and 6 of Bax can independently form large lipid pores pdf
... and NMRstructure of human Bcl-xL, an inhibitor of programmedcell death. Nature 381, 335–341.25 Suzuki M, Youle RJ & Tjandra N (2000) Structure of bax. Coregulation of dimer formation and ... smaller and do not needthe concerted action of tBid. These data indicate that the sequences of bothfragments of the hairpin contain the principal physicochemical require-ments for pore formation, ... structure of water-soluble forms of a number of Bcl2 proteins is known (see, for example [24,25]). Themost characteristic feature of this structure is a dou-ble-helix hairpin buried in the core of...
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